N1-[4-methoxy-2-(trifluoromethyl)phenyl]-2-[3-chloro-3-(4-chlorophenyl)prop-2-enylidene]hydrazine-1-carbothioamide CAS 680212-21-9
| CAS No. | 680212-21-9 |
| Molecular Formula | C18H14Cl2F3N3OS |
| Molecular Weight | 448.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N1-[4-methoxy-2-(trifluoromethyl)phenyl]-2-[3-chloro-3-(4-chlorophenyl)prop-2-enylidene]hydrazine-1-carbothioamide (CAS 680212-21-9), a certified reference material (molecular formula C18H14Cl2F3N3OS, MW 448.29 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N1-[4-methoxy-2-(trifluoromethyl)phenyl]-2-[3-chloro-3-(4-chlorophenyl)prop-2-enylidene]hydrazine-1-carbothioamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 448.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N1-[4-methoxy-2-(trifluoromethyl)phenyl]-2-[3-chloro-3-(4-chlorophenyl)prop-2-enylidene]hydrazine-1-carbothioamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14Cl2F3N3OS |
| Molecular Weight | 448.29 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(4-methoxy-2-nitrophenyl)-N-(phenylsulfonyl)benzenesulfonamide (CAS 159383-46-7)
- 1-Methoxy-1-oxopropan-2-yl 5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrobenzoate (CAS 77509-33-2)
- 3-Methoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide (CAS 925437-59-8)
- Ethyl 6-(2-methoxy-2-oxoethyl)-4-((4-methoxyphenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate (CAS 866134-49-8)
- 4-Methoxy-N-{2,5,6-trimethyl-1-[(3-methylphenyl)methyl]-1H-1,3-benzodiazol-4-yl}benzene-1-sulfonamide (CAS 338964-16-2)
- 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 2-chlorobenzoate (CAS 477889-71-7)
- 4-[3-Methoxy-3-oxo-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propyl]phenyl 4-chlorobenzoate (CAS 477890-05-4)
- 7-Methoxy-2,2-dimethylchroman-6-yl palmitate (CAS 1105025-85-1)
Recommended Standards
- Methyl 4-(2-((5-(4-bromophenyl)-1,3,4-oxadiazol-2-yl)thio)acetamido)benzoate (CAS 332161-22-5)
- 5-((2,6-Dimethylmorpholino)methyl)-2-(3-iodophenyl)benzo[d]oxazole (CAS 1706441-07-7)
- 2-((3-Cyano-6-ethyl-5-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)-N-(2,6-dichlorophenyl)acetamide (CAS 664999-18-2)
- 4-[3-(2,6-Dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-N-[(oxolan-2-yl)methyl]-1H-pyrrole-2-carboxamide (CAS 866049-51-6)
- Ethyl 3-(furan-3-yl)-1-methyl-1H-pyrazole-4-carboxylate (CAS 2377991-46-1)
- Ethyl 2-amino-2-(thiophen-2-yl)acetate (CAS 154410-94-3)
- 1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl-d4]-α,α-diphenyl-3-pyrrolidineacetonitrile (CAS 1216586-32-1)
- 2-Amino-1,1,1,7,7,7-hexafluoro-6-hydroxy-2,6-bis(trifluoromethyl)-4-(isopropylimino)heptane (CAS 723294-77-7)
- 1-(4-Fluorophenyl)-3-(phenylamino)pyrrolidine-2,5-dione (CAS 142014-00-4)
- 5-(4-Chlorophenyl)-4h-1,2,4-triazol-3-amine nitrate (CAS 1417568-97-8)
- 3-Methyl-3-aza-bicyclo[3.2.1]oct-8-ylamine (CAS 108640-12-6)
- 1-Cyclopropyl-1-methylguanidine hydrochloride (CAS 1423026-93-0)
- methyl 2-amino-4-methanesulfonylbenzoate (CAS 158580-87-1)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
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