N-(But-3-yn-1-yl)-2-chloro-N-phenylacetamide CAS 111631-63-1
| CAS No. | 111631-63-1 |
| Molecular Formula | C12H12ClNO |
| Molecular Weight | 221.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies N-(But-3-yn-1-yl)-2-chloro-N-phenylacetamide (CAS 111631-63-1), a certified reference material (molecular formula C12H12ClNO, MW 221.68 g/mol) for analytical method development and quality control.
The molecular framework of N-(But-3-yn-1-yl)-2-chloro-N-phenylacetamide (C12H12ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H12ClNO |
| Molecular Weight | 221.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-(Chloromethyl)-5-(2,5-dimethylphenyl)oxazole (CAS 1094382-39-4)
- 2-Chloro-1-(2,7-dimethyl-1H-indol-3-yl)ethanone (CAS 1134334-67-0)
- 2-(Chloromethyl)-5-(4-ethylphenyl)-1,3-oxazole (CAS 1094226-54-6)
- 4-Chloro-6-isopropoxyquinoline (CAS 1153083-63-6)
- H-D-Hyp(tBu)-OH (CAS CATO-CPTD788512)
- (±)-1-Phenylethyl Alcohol (CAS 98-85-1)
- 2,2'-Diethynyl-1,1'-biphenyl (CAS 18442-29-0)
- N-Methylcyclopentanecarboxamide (CAS 4492-50-6)
- 2-[(4-Bromophenyl)amino]acetic acid (CAS 13370-62-2)
- 4-(Chloromethyl)-2-(pyridin-2-yl)thiazole, 97% (CAS 342025-41-6)
- (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 299898-52-5)
- 1-(2,4-Dichloro-6-hydroxyphenyl)ethanone (CAS 57051-50-0)
- N-((3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl)propan-2-amine (CAS 1156806-31-3)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com