Bexagliflozin Impurity 9 CAS 1118567-45-5
| CAS No. | 1118567-45-5 |
| Molecular Formula | C18H18BrClO2 |
| Molecular Weight | 381.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bexagliflozin Impurity 9 (C18H18BrClO2) contains a steroid core, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Bexagliflozin Impurity 9 (CAS 1118567-45-5) is a certified pharmaceutical impurity reference standard with the molecular formula C18H18BrClO2 and a molecular weight of 381.69 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bexagliflozin Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18BrClO2 |
| Molecular Weight | 381.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 98% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl/Br-containing |
Related Bexagliflozin Standards
- Bexagliflozin Impurity 7 (CAS CATO-C4X-33227)
- Bexagliflozin Impurity 6 (CAS CATO-C4X-33226)
- Bexagliflozin (CAS 1118567-05-7)
- Bexagliflozin Impurity 11 (CAS CATO-C4X-332211)
- Bexagliflozin Impurity 12 (CAS CATO-C4X-332212)
- Bexagliflozin Impurity 13 (CAS CATO-C4X-332213)
- Bexagliflozin Impurity 3 (CAS CATO-C4X-33223)
- Bexagliflozin Impurity 4 (CAS CATO-C4X-33224)
Recommended Standards
- Empagliflozin Impurity 279 (CAS CATO-C4X-1065279)
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- Empagliflozin Impurity 277 (CAS CATO-C4X-1065277)
- 4-(4-Nitro-2-(trifluoromethyl)phenoxy)benzenesulfonyl chloride (CAS 1858255-92-1)
- Loxoprofen impurity 120 (CAS CATO-C4X-1488120)
- Palbociclib Impurity 106 TFA salt (CAS CATO-C4X-1125106)
- Chlorprothixene EP Impurity D Oxalate (CAS 1082649-26-0（free base）)
- n-(1-Hydroxy-2-oxo-2-phenylethyl)acetamide (CAS 2187-27-1)
- 2-((Benzoyloxy)methyl)benzoic acid (CAS 58249-83-5)
- 2,2,5-trimethyl-2,3-dihydroquinazolin-4(1H)-one (CAS 1050885-58-9)
- 2-(3-Bromophenyl)-1H-indole-3-carbaldehyde (CAS 1098340-34-1)
- Piperidine-2,2,6,6-d4 (CAS 1001337-60-5)
- (2-(Bromomethyl)benzo[d]oxazol-4-yl)methanamine (CAS 1806318-15-9)
- Peptide Impurity 82 (CAS 10491-78-8)
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