Quetiapine EP Impurity B Dihydrochloride CAS 111974-74-4
| CAS No. | 111974-74-4 |
| Molecular Formula | C17H17N3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Quetiapine EP Impurity B Dihydrochloride (CAS 111974-74-4), a pharmacopoeial impurity reference standard (molecular formula C17H17N3SHCl, MW 331.86 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, Quetiapine EP Impurity B Dihydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 331.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Quetiapine EP Impurity B Dihydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H17N3S 2*HCl |
| Molecular Weight | 331.86 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Quetiapine Standards
- Quetiapine Carboxylate Impurity (CAS 1011758-00-1)
- Quetiapine EP Impurity P (CAS 1011758-03-4)
- Quetiapine EP Impurity P Hemifumarate (CAS 1011758-03-4（free base）)
- Quetiapine Impurity 56 (CAS 1015-89-0)
- Quetiapine Impurity N3 (CAS 102893-57-2)
- Quetiapine-d8 HemifumarateDISCONTINUED. Please see Q510002. (CAS 1031703-36-2)
- Quetiapine EP Impurity H (CAS 1076199-40-0)
- Quetiapine (CAS 111974-69-7)
Recommended Standards
- Ambroxol Impurity 34 HCl (CAS CATO-C4X-108534)
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- N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(piperazin-1-yl)acetamide (CAS 141400-73-9)
- N-(2-Aminoethyl)-2-nitroaniline hydrochloride (CAS 86419-71-8)
- 3-Chloro-1-(4-isopentylpiperazin-1-yl)propan-1-one (CAS 1178290-72-6)
- 5-(3-Fluorocyclobutyl)-1H-pyrazol-3-amine (CAS 2228036-45-9)
- Endo-Gly29-Tirzepatide (CAS CATO-CPTD788685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com