5,8-Epoxy-13-cis Retinoic Acid (Mixture of Diastereomers) CAS 112018-12-9

Purity ≥95%In StockPharmaceutical Standards
CAS No.112018-12-9
Molecular FormulaC20H28O3
Molecular Weight316.43 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5,8-Epoxy-13-cis Retinoic Acid (Mixture of Diastereomers) CAS 112018-12-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5,8-Epoxy-13-cis Retinoic Acid (Mixture of Diastereomers).

CATO supplies 5,8-Epoxy-13-cis Retinoic Acid (Mixture of Diastereomers) (CAS 112018-12-9), a certified reference material (molecular formula C20H28O3, MW 316.43 g/mol) for analytical method development and quality control.

The molecular framework of 5,8-Epoxy-13-cis Retinoic Acid (Mixture of Diastereomers) (C20H28O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC20H28O3
Molecular Weight316.43 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989

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