Gadobutrol Impurity 104 4HCl CAS 112193-75-6（free base）
| CAS No. | 112193-75-6（free base） |
| Molecular Formula | C12H24N4O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Gadobutrol Impurity 104 4HCl (CAS 112193-75-6（free base）) is a certified pharmaceutical impurity reference standard with the molecular formula C12H24N4O4HCl and a molecular weight of 324.81 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Gadobutrol Impurity 104 4HCl is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 324.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H24N4O4 4*HCl |
| Molecular Weight | 324.81 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Gadobutrol Standards
- Gadobutrol Impurity 112 (CAS 1003-83-4)
- Gadobutrol Impurity 12 4HCl (CAS 10045-25-7)
- Gadobutrol Impurity 79 (CAS 105855-71-8)
- Gadobutrol Impurity 115 (CAS 112-24-3)
- Gadobutrol EP Impurity C (Gadoteridol USP Related Compound B) (CAS 112188-16-6)
- Gadobutrol Impurity N5 (CAS 112193-75-6)
- Gadobutrol Impurity 37 (Cyclen Disulfate) (CAS 112193-77-8)
- Gadobutrol Impurity 103 Trifluoroacetic acid (CAS 114873-37-9（free base）)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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