2,5-Dichloro-p-xylene CAS 1124-05-6
| CAS No. | 1124-05-6 |
| Molecular Formula | C8H8Cl2 |
| Molecular Weight | 175.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,5-Dichloro-p-xylene.
2,5-Dichloro-p-xylene (CAS 1124-05-6) is a high-purity analytical reference standard with the molecular formula C8H8Cl2 and a molecular weight of 175.06 g/mol.
The molecular framework of 2,5-Dichloro-p-xylene (C8H8Cl2) is characterized by chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,5-Dichloro-p-xylene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8Cl2 |
| Molecular Weight | 175.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Dichloro Standards
- 1,2-Dichloro-3,4-dimethylbenzene (CAS 68266-67-1)
- 1,2-Dichloro-3-ethylbenzene (CAS 54484-61-6)
- 1,2-Dichloro-4,5-dimethylbenzene (CAS 20824-80-0)
- 1,3-Dichloro-2-ethylbenzene (CAS 33407-02-2)
- 1,4-Dichloro-2-ethylbenzene (CAS 54484-63-8)
- 1,5-Dichloro-2,3-dimethylbenzene (CAS 70172-92-8)
- 1,5-Dichloro-2,4-dimethylbenzene (CAS 2084-45-9)
- 2,4-Dichloro-1-ethylbenzene (CAS 54484-62-7)
Recommended Standards
- Mianserin impurity 02 (CAS 1074-11-9)
- 4-Bromotoluene-2,3,5,6-d4 (CAS 112484-85-2)
- 1-Chloro-2-(2-chloroethyl)benzene (CAS 1005-06-7)
- 2-Chloro-1-(chloromethyl)-3-methylbenzene (CAS 1261581-40-1)
- (1-(2-Fluorophenyl)-3-(pyridin-3-yl)-1H-pyrazol-4-yl)methanol (CAS 618383-42-9)
- 3-methylpyridazin-4-amine hydrochloride (CAS 1443980-51-5)
- Ethyl 2-(6-methylpyridin-3-yl)cyclopropane-1-carboxylate (CAS 1251905-92-6)
- 2-(2-Bromo-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1595078-06-0)
- 4,5-Dimethylpyridine-3-sulfonic acid (CAS 1160993-91-8)
- 3-Bromo-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid (CAS 1780376-28-4)
- Imatinib EP Impurity D (CAS 1821122-73-9)
- (S)-1-(3-chloro-4-(trifluoromethyl)phenyl)-2-methoxyethan-1-amine (CAS 1270272-46-2)
- 2,3-Diphenylbenzofuran-7-ol (CAS 29938-00-9)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
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