Mianserin impurity 02 CAS 1074-11-9
| CAS No. | 1074-11-9 |
| Molecular Formula | C8H8Cl2 |
| Molecular Weight | 175.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Mianserin impurity 02 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Mianserin impurity 02 (CAS 1074-11-9, C8H8Cl2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Mianserin impurity 02 (C8H8Cl2) contains chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 175.06 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H8Cl2 |
| Molecular Weight | 175.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Mianserin Standards
- Mianserin impurity 45 (CAS CATO-C4X-136945)
- Mianserin Impurity 80 (CAS 1260761-23-6)
- Mianserin Impurity 114 (CAS 1314960-88-7)
- Mianserin Impurity 109 (CAS 4397-15-3)
- Mianserin Impurity 62 (CAS CATO-C4X-136962)
- Mianserin Impurity 117 (CAS 6407-17-6)
- Mianserin impurity 01 (CAS 6853-14-1)
- Mianserin Impurity 56 (CAS 68998-54-9)
Recommended Standards
- 1-Chloro-2-(2-chloroethyl)benzene (CAS 1005-06-7)
- 2,5-Dichloro-p-xylene (CAS 1124-05-6)
- Selenophene-3-carboxylic acid (CAS 35577-09-4)
- 4-Bromotoluene-2,3,5,6-d4 (CAS 112484-85-2)
- Progesterone Impurity 71 (CAS CATO-C4X-150271)
- Sitafloxacin Isomer Impurity 7(SSS) (CAS CATO-C4X-11557)
- Daprodustat Impurity 12 (CAS 10468-40-3)
- 4-Methoxy-5-nitro-1H-pyridin-2-one (CAS 607373-82-0)
- 2-Methyl-1H-pyrrolo[3,2-b]pyridine-5-carbonitrile (CAS 1190318-13-8)
- Siduron (CAS 1982-49-6)
- (2R,3R,4S,5R)-2-(4-(dimethylamino)-5-methylpyrrolo[2',3':4,5]pyrrolo[2,3-d]pyrimidin-8(5H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 2180983-51-9)
- 2-(4-Bromo-2-formylphenoxy)-N-(2,5-dimethylphenyl)acetamide (CAS 552841-81-3)
- (S)-2-(2-((Benzyl(cyclopropyl)amino)methyl)pyrrolidin-1-yl)ethanol (CAS 1354009-65-6)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
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