Imatinib Impurity 18 CAS 112696-91-0
| CAS No. | 112696-91-0 |
| Molecular Formula | C16H15N5 |
| Molecular Weight | 277.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Imatinib Impurity 18 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Imatinib Impurity 18 (CAS 112696-91-0, C16H15N5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, Imatinib Impurity 18 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 277.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Imatinib Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H15N5 |
| Molecular Weight | 277.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 5 |
Related Imatinib Standards
- Imatinib EP Impurity F (CAS 6515-58-8)
- Imatinib EP Impurity F (CAS 152460-10-1)
- Imatinib Impurity 69 (CAS 404577-34-0)
- Imatinib Impurity 42 (CAS 67013-55-2)
- Imatinib Impurity 71 (CAS 2118894-75-8)
- Imatinib Impurity 25 (CAS CATO-C4X-106825)
- Imatinib Impurity 19 (CAS 3367-50-8)
- Imatinib Impurity 84 (CAS CATO-C4X-106884)
Recommended Standards
- Ivabradine Impurity 20 (CAS 1235547-06-4)
- Methyl 4-((tert-butoxycarbonyl)amino)cubane-1-carboxylate (CAS 883554-71-0)
- Ivabradine impurity 92 (CAS CATO-C4X-111992)
- 98166-08-6 2-Propenoic acid, 2-((2,6-dimethylphenyl)amino)-, methyl ester Methyl 2-(2,6-dimethylanilino)prop-2-enoate (CAS 98166-08-6)
- Febuxostat Impurity 5 (CAS 7133-90-6)
- Cefcapene Impurity 40 (CAS CATO-C4X-182440)
- Oryzanol Impurity 17 (CAS 286011-27-6)
- 1H-Benzo[4,5]imidazo[2,1-c][1,2,4]triazol-3-ol (CAS 116577-81-2)
- 2-(3-Ethylbenzo[d]thiazol-2(3H)-ylidene)acetaldehyde (CAS 41471-32-3)
- 2-Methyl-5-phenylisoxazolidine (CAS 68408-65-1)
- [(2,3-dimethoxyphenyl)methyl][(pyridin-3-yl)methyl]amine (CAS 355383-37-8)
- Minocycline EP Impurity G DiTFA salt (CAS 601455-95-2(free base))
- 2-(4-Methyl-1H-pyrazol-3-yl)-1-morpholinoethanethione (CAS 806637-95-6)
- Des-Val23-Tirzepatide (CAS CATO-CPTD788950)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com