Imatinib Impurity 71 CAS 2118894-75-8
| CAS No. | 2118894-75-8 |
| Molecular Formula | C16H20N4O |
| Molecular Weight | 284.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Imatinib Impurity 71.
As a process- or degradation-related impurity, Imatinib Impurity 71 (CAS 2118894-75-8, C16H20N4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Imatinib Impurity 71 (C16H20N4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Imatinib Impurity 71 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H20N4O |
| Molecular Weight | 284.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 4 |
Related Imatinib Standards
- Imatinib Impurity 69 (CAS 404577-34-0)
- Imatinib Impurity 25 (CAS CATO-C4X-106825)
- Imatinib EP Impurity F (CAS 6515-58-8)
- Imatinib EP Impurity F (CAS 152460-10-1)
- Imatinib Impurity 18 (CAS 112696-91-0)
- Imatinib Impurity 42 (CAS 67013-55-2)
- Imatinib Impurity 19 (CAS 3367-50-8)
- Imatinib Impurity 8 (CAS 2410195-20-7)
Recommended Standards
- N-(2-Morpholinoethyl)-6-phenylpyrimidin-4-amine (CAS 914217-63-3)
- Teneligliptin impurity 22 (CAS 1453906-29-0)
- n-(1-Benzylpiperidin-4-yl)-1h-imidazole-1-carboxamide (CAS 380222-80-0)
- Sulfaethylthiadiazole (CAS 94-19-9)
- Sildenafil Impurity 51 (CAS 263897-18-3)
- Parecoxib Impurity 47 (CAS 181695-84-1)
- Lifitegrast Impurity N12 (CAS 851785-70-1)
- (4-Bromophenyl)(cycloheptyl)methanol (CAS 1247638-58-9)
- Propanoic acid, 3-(dodecylthio)-, 1,1'-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)] ester (CAS 64253-30-1)
- Tert-butyl 4-(1-benzyl-2-oxo-1,2,3,4-tetrahydroquinazolin-5-yl)piperazine-1-carboxylate (CAS 1296346-81-0)
- N-{[(2,6-Dimethylanilino)carbonyl]oxy}-N-{(E)-2,2-dimethyl-1-[(2-nitrophenoxy)methyl]propylidene}amine (CAS 478043-12-8)
- 4-Methyl-1,2,3-thiadiazol-5-amine (CAS 6440-01-3)
- 2-(4-Hexyloxybenzoyl)-6-methoxypyridine (CAS 1187166-42-2)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
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