4-Benzoyl-6-chloro-2-methylisoquinolin-3(2H)-one CAS 112780-92-4
| CAS No. | 112780-92-4 |
| Molecular Formula | C17H12ClNO2 |
| Molecular Weight | 297.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Benzoyl-6-chloro-2-methylisoquinolin-3(2H)-one.
4-Benzoyl-6-chloro-2-methylisoquinolin-3(2H)-one (CAS 112780-92-4) is a high-purity analytical reference standard with the molecular formula C17H12ClNO2 and a molecular weight of 297.74 g/mol.
4-Benzoyl-6-chloro-2-methylisoquinolin-3(2H)-one (C17H12ClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Benzoyl-6-chloro-2-methylisoquinolin-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12ClNO2 |
| Molecular Weight | 297.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-(4-Chlorophenyl)-8-methylquinoline-4-carboxylic acid (CAS 107027-43-0)
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- 2-(2-Chlorophenyl)-8-methylquinoline-4-carboxylic acid (CAS 107027-38-3)
- 2-(3-Methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160264-60-7)
- 2-Methyl-1-(3-methylbenzoyl)piperazine (CAS 1240565-95-0)
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- (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(aminomethyl)tetrahydrofuran-3-ol (CAS 14585-60-5)
- 5-Chloro-6-(trifluoromethyl)pyrimidin-4-amine (CAS 1260763-88-9)
- Fluoxetine Impurity 13 (CAS CATO-C4X-135213)
- 2-(4-Benzyl-1-piperazinyl)nicotinic acid (CAS 247117-48-2)
- 2-Bromo-6-cyano-4-nitrophenyl acetate (CAS 1071407-19-6)
- 1,2,4,5-Tetraazaspiro[5.5]Undecane-3-thione (CAS 18801-59-7)
- 5-Isopropyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-amine (CAS 2170752-19-7)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
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