(2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(aminomethyl)tetrahydrofuran-3-ol CAS 14585-60-5

Purity 97%+In StockPharmaceutical Standards
CAS No.14585-60-5
Molecular FormulaC10H14N6O2
Molecular Weight250.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(aminomethyl)tetrahydrofuran-3-ol CAS 14585-60-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(aminomethyl)tetrahydrofuran-3-ol.

CATO supplies (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(aminomethyl)tetrahydrofuran-3-ol (CAS 14585-60-5), a certified reference material (molecular formula C10H14N6O2, MW 250.26 g/mol) for analytical method development and quality control.

The molecular framework of (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(aminomethyl)tetrahydrofuran-3-ol (C10H14N6O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(aminomethyl)tetrahydrofuran-3-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H14N6O2
Molecular Weight250.26 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Nitrogen Atoms6

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