Ethyl 1-(6-chloropyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate CAS 1128268-00-7
| CAS No. | 1128268-00-7 |
| Molecular Formula | C12H9ClF3N3O2 |
| Molecular Weight | 319.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 319.67 g/mol gives Ethyl 1-(6-chloropyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 1-(6-chloropyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 1128268-00-7), molecular formula C12H9ClF3N3O2 and molecular weight 319.67 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 1-(6-chloropyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (C12H9ClF3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 319.67 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9ClF3N3O2 |
| Molecular Weight | 319.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- (4-(6-Chloropyridin-2-yl)piperazin-1-yl)(4-fluorophenyl)methanone (CAS 339107-32-3)
- 1-Benzyl-2-(2-chloropyridin-3-yl)-1H-benzo[d]imidazole (CAS 338411-19-1)
- (3-((6-Chloropyridin-2-yl)oxy)phenyl)(morpholino)methanone (CAS 866150-73-4)
- Ethyl 2-(3-chloropyridin-2-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylate (CAS 1431729-27-9)
- N'-(6-chloropyridin-2-yl)-2-(2-nitroethyl)benzohydrazide (CAS 338410-33-6)
- 1-[(6-Chloropyridin-3-yl)methyl]-4-(4-methoxyphenyl)piperazine (CAS 478048-49-6)
- 1-(3-Chloropyridin-2-yl)-3-(2,2,2-trifluoroethoxy)-1H-pyrazole-5-carboxylic acid (CAS 500011-97-2)
- N-((2-chloropyridin-3-yl)carbamothioyl)-2-methoxybenzamide (CAS 866014-53-1)
Recommended Standards
- 4-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]-N-(2,2,2-trifluoroethyl)benzamide (CAS 1119449-64-7)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 1420776-15-3)
- 1-[4-Chloro-3-(trifluoromethyl)phenyl]-5-ethyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1096912-00-3)
- Ethyl 2-(2-chlorophenyl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylate (CAS 1431729-86-0)
- 2,3-Dimethoxyaniline (CAS 6299-67-8)
- 1-(2-Fluoroethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1905405-89-1)
- 4-Nitro-2-(phenylamino)benzoic acid (CAS 49551-01-1)
- 477852-33-8 6-[(4-chlorophenyl)sulfanyl]imidazo[2,1-b][1,3]thiazole-5-carbonitrile KS-00002YTT (CAS 477852-33-8)
- 4-Amino-2,6-dichloro-3-nitropyridine (CAS 2897-43-0)
- 4-Chloro-3-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)benzoic acid (CAS 380337-05-3)
- 4-Aminonaphthalene-1,2-dione hemihydrate (CAS 20814-38-4)
- 4,4,4-Trifluoro-1-morpholinobutane-1,3-dione (CAS 338792-91-9)
- N,N-Dimethyl-2-(3-nitro-1H-pyrazol-1-yl)acetamide (CAS 1343183-73-2)
- Tripeptide-10 citrulline (CAS 960531-53-7)
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