(2R)-2-(hydroxymethyl)-2H-furan-5-one CAS 112837-17-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2R)-2-(hydroxymethyl)-2H-furan-5-one.

(2R)-2-(hydroxymethyl)-2H-furan-5-one (CAS 112837-17-9) is a high-purity analytical reference standard with the molecular formula C5H6O3 and a molecular weight of 114.10 g/mol.

Structurally, (2R)-2-(hydroxymethyl)-2H-furan-5-one (C5H6O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 114.10 g/mol, it falls into the low-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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