2,3-Dihydrobenzofuran-5-sulfonamide CAS 112894-47-0
| CAS No. | 112894-47-0 |
| Molecular Formula | C8H9NO3S |
| Molecular Weight | 199.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,3-Dihydrobenzofuran-5-sulfonamide (CAS 112894-47-0), molecular formula C8H9NO3S and molecular weight 199.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,3-Dihydrobenzofuran-5-sulfonamide (C8H9NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9NO3S |
| Molecular Weight | 199.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dihydrobenzofuran Standards
- 1-(2,3-Dihydrobenzofuran-5-yl)-2,2-difluoroethan-1-one (CAS 1378814-93-7)
- 3-(2,3-Dihydrobenzofuran-2-yl)pyridine (CAS 866474-85-3)
- 4-(2,3-Dihydrobenzofuran-2-yl)pyridine (CAS 866474-84-2)
- 2-Methyl-2,3-dihydrobenzofuran-7-carbonyl chloride (CAS 103261-01-4)
- 5-Methyl-2,3-dihydrobenzofuran-7-carbonyl chloride (CAS 103261-02-5)
- 3-(2,3-Dihydrobenzofuran-5-yl)isoxazol-5-amine (CAS 1250709-84-2)
- 2-Phenyl-2,3-dihydrobenzofuran (CAS 55962-04-4)
- 1-(2,3-Dihydrobenzofuran-2-yl)pent-4-en-1-one (CAS 1566883-08-6)
Recommended Standards
- 5-(Acetamidomethyl)thiophene-2-carboxylic acid (CAS 1114822-83-1)
- 1,3-Dihydroisobenzofuran-5-sulfonamide (CAS 1189378-81-1)
- 2-(2-Mercapto-6-oxo-1,6-dihydropyrimidin-4-yl)-N-methylacetamide (CAS 1105191-77-2)
- N-Ethoxy-N-(2-formylthiophen-3-yl)formamide (CAS 122805-79-2)
- 1-(3,4-Dimethoxybenzyl)-3,5-dimethyl-4-nitro-1h-pyrazole (CAS 957320-38-6)
- 263764-83-6 7H-3a,7-Epoxyfuro[2,3-d]oxepin-2(3H)-one, tetrahydro-7-methyl-,(3aR,7S,8aR)- (CAS 263764-83-6)
- Benzo[d]oxazol-5-ylmethanamine (CAS 903556-78-5)
- Sivelestat sodium impurity 44 (CAS CATO-C4X-212344)
- n-(2-Methoxyethyl)tetrahydro-2h-pyran-4-amine (CAS 887588-98-9)
- 2-(Piperazin-1-ylmethyl)benzonitrile hydrochloride (CAS 1289388-18-6)
- (E)-5-Methylhex-3-en-2-one (CAS 1821-29-0)
- BDP TMR amine HCl (CAS 2183473-09-6)
- 2-{2-[4-(3-nitrophenyl)piperazin-1-yl]ethyl}-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one (CAS 1263386-35-1)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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