5-(5-(2-Chloro-5-iodobenzyl)thiophen-2-yl)-2-fluoropyridine CAS 1131770-46-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1131770-46-1
Molecular FormulaC16H10ClFINS
Molecular Weight429.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(5-(2-Chloro-5-iodobenzyl)thiophen-2-yl)-2-fluoropyridine CAS 1131770-46-1 chemical structure

Description

5-(5-(2-Chloro-5-iodobenzyl)thiophen-2-yl)-2-fluoropyridine (CAS 1131770-46-1), molecular formula C16H10ClFINS and molecular weight 429.68 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine/iodine substitution, 5-(5-(2-Chloro-5-iodobenzyl)thiophen-2-yl)-2-fluoropyridine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 429.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(5-(2-Chloro-5-iodobenzyl)thiophen-2-yl)-2-fluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H10ClFINS
Molecular Weight429.68 g/mol
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Cl/I-containing
Nitrogen Atoms1
Sulfur Atoms1

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