| CAS No. | 1131770-46-1 |
| Molecular Formula | C16H10ClFINS |
| Molecular Weight | 429.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
5-(5-(2-Chloro-5-iodobenzyl)thiophen-2-yl)-2-fluoropyridine (CAS 1131770-46-1), molecular formula C16H10ClFINS and molecular weight 429.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine/iodine substitution, 5-(5-(2-Chloro-5-iodobenzyl)thiophen-2-yl)-2-fluoropyridine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 429.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(5-(2-Chloro-5-iodobenzyl)thiophen-2-yl)-2-fluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C16H10ClFINS |
| Molecular Weight | 429.68 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |