7-Chloro-3-(2,4-dichloro-5-isopropoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one CAS 339099-18-2
| CAS No. | 339099-18-2 |
| Molecular Formula | C18H15Cl3N2O2S |
| Molecular Weight | 429.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Chloro-3-(2,4-dichloro-5-isopropoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one.
7-Chloro-3-(2,4-dichloro-5-isopropoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one (CAS 339099-18-2), molecular formula C18H15Cl3N2O2S and molecular weight 429.75 g/mol, is a CATO reference standard with documented purity and traceability.
7-Chloro-3-(2,4-dichloro-5-isopropoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one (C18H15Cl3N2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-3-(2,4-dichloro-5-isopropoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15Cl3N2O2S |
| Molecular Weight | 429.75 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- N-(4-chloro-3-nitrophenyl)-4-[3-(trifluoromethyl)pyridin-2-yl]tetrahydropyrazine-1(2H)-carboxamide (CAS 260798-64-9)
- 5-Chloro-3,4-bis(((4-chlorophenyl)thio)methyl)-1-methyl-1H-pyrazole (CAS 318234-29-6)
- 5-Chloro-4-(((3-chlorophenyl)thio)methyl)-3-(((4-chlorophenyl)thio)methyl)-1-methyl-1H-pyrazole (CAS 318234-33-2)
- 5-Chloro-4-{[(2,3-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-[(phenylsulfanyl)methyl]-1H-pyrazole (CAS 318248-73-6)
- 5-Chloro-4-{[(2,6-dichlorophenyl)sulfanyl]methyl}-1-methyl-3-[(phenylsulfanyl)methyl]-1H-pyrazole (CAS 318248-72-5)
- 5-Chloro-4-{[(2-chlorophenyl)sulfanyl]methyl}-3-{[(4-chlorophenyl)sulfanyl]methyl}-1-methyl-1H-pyrazole (CAS 318234-34-3)
- 5-(5-(2-Chloro-5-iodobenzyl)thiophen-2-yl)-2-fluoropyridine (CAS 1131770-46-1)
- 1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose (CAS 3601-90-9)
Recommended Standards
- 7,9-Dichloro-5-(4-chlorophenyl)-2-phenyl-5,10b-dihydro-1H-benzo[e]pyrazolo[1,5-c][1,3]oxazine (CAS 302913-77-5)
- 1,1'-Diiodoferrocene (CAS 12145-93-6)
- 2-[(3-Chlorophenyl)methyl]-4-[(2,6-dichlorophenyl)methoxy]quinazoline (CAS 400078-64-0)
- 2,4,5-Trichlorophenyl 4-(octyloxy)benzoate (CAS 79404-93-6)
- 4-Oxo-1,4-dihydropyridine-3-carbonitrile (CAS 100367-56-4)
- 1-Neopentyl-5-phenyl-1H-imidazole (CAS 116145-77-8)
- 2-Fluoro-N-isobutylbenzamide (CAS 330469-13-1)
- 4,4,9,9-tetrakis(4-hexylphenyl)-4,9-dihydro-s-indeno[1,2-b:5,6-b']dithiophene-2,7-di aldehyde (CAS 1884694-93-2)
- Palbociclib Impurity 122 (CAS CATO-C4X-1125122)
- DSRM-3716 (CAS 58142-99-7)
- (S)-DIHYDROPYRROLO[1,2-C]OXAZOLE-3,6(1H,5H)-DIONE (CAS 1447615-97-5)
- N-Benzyl-6-(pyridin-4-yl)imidazo[1,2-a]pyrazin-8-amine (CAS 915373-27-2)
- 5-Iodo-1-methyl-1H-benzo[d]imidazole (CAS 705262-59-5)
- Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 330456-24-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com