4-Chloro-3-fluoropyridine-2-methanol CAS 113209-83-9
| CAS No. | 113209-83-9 |
| Molecular Formula | C6H5ClFNO |
| Molecular Weight | 161.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Chloro-3-fluoropyridine-2-methanol (CAS 113209-83-9), a certified reference material (molecular formula C6H5ClFNO, MW 161.56 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-3-fluoropyridine-2-methanol (C6H5ClFNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-3-fluoropyridine-2-methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5ClFNO |
| Molecular Weight | 161.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-5-fluoro-3-methoxypyridine (CAS 1097264-89-5)
- 4-Chloro-5-fluoro-2-methylpyridine, N-oxide (CAS 113209-89-5)
- 4-Chloro-5-fluoro-2-pyridinemethanol (CAS 113209-90-8)
- 3-Chloro-2-fluoro-4-(hydroxymethyl)pyridine (CAS 1149587-00-7)
- (6-Chloro-5-fluoropyridin-3-yl)methanol (CAS 1174028-24-0)
- 2-Chloro-3-fluoro-4-methoxypyridine (CAS 1184172-10-8)
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- 5-Chloro-2-fluoro-4-methoxypyridine (CAS 1211537-31-3)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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