Ivabradine impurity 90 CAS 1132667-04-9
| CAS No. | 1132667-04-9 |
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Ivabradine impurity 90 (CAS 1132667-04-9) is a certified pharmaceutical impurity reference standard with the molecular formula C12H17NO2 and a molecular weight of 207.27 g/mol.
Structurally, Ivabradine impurity 90 (C12H17NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 207.27 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Ivabradine impurity 90 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
Related Ivabradine Standards
- Ivabradine Impurity 17 (CAS 866783-12-2)
- Ivabradine Impurity 76 (CAS 55171-70-5)
- Ivabradine Impurity 53 (CAS CATO-C4X-111953)
- Ivabradine impurity 86 (CAS 1220993-44-1)
- Ivabradine Impurity 26 (CAS 20925-64-8)
- Ivabradine Impurity 25 HCl (CAS 1132079-01-6)
- Ivabradine Impurity 16 (CAS 73344-75-9)
- Ivabradine Impurity 65 (CAS 2387117-59-9)
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