Salbutamol Impurity 177 CAS CATO-C4X-1176177
| CAS No. | CATO-C4X-1176177 |
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Salbutamol Impurity 177 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Salbutamol Impurity 177 (CAS CATO-C4X-1176177), a pharmacopoeial impurity reference standard (molecular formula C12H17NO2, MW 207.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Salbutamol Impurity 177 (C12H17NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Salbutamol Impurity 177 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Salbutamol Standards
- Salbutamol EP Impurity H (CAS 132183-64-3)
- Salbutamol Impurity 194 (CAS CATO-C4X-1176194)
- Salbutamol Impurity 77 (CAS 39235-57-9)
- Salbutamol EP Impurity B (CAS 96948-64-0)
- Salbutamol Glyoxal Impurity (CAS 72189-44-7)
- Salbutamol Glyoxal Impurity (CAS CATO-C4X-1176167)
- R-Salbutamol Glyoxal Impurity (CAS CATO-C4X-1176205)
- Salbutamol Impurity 38 (CAS CATO-C4X-117638)
Recommended Standards
- Arbidol Impurity 27 (CAS CATO-C4X-112927)
- Terbutaline Impurity 44 (CAS 2095852-55-2)
- Ivabradine impurity 90 (CAS 1132667-04-9)
- Indobufen Impurity 45 (CAS CATO-C4X-179245)
- Dexamethasone impurity 91 (CAS CATO-C4X-116591)
- Testosterone Impurity 5 (CAS CATO-C4X-24325)
- Aztreonam Dimer Impurity 36 (CAS CATO-C4X-152236)
- 3-Chloro-2-(1-(4-methyl-5-(methylthio)-4H-1,2,4-triazol-3-yl)ethyl)-5-(trifluoromethyl)pyridine (CAS 339010-64-9)
- Poly(perfluoropropylene Oxide) (CAS 25038-02-2)
- 3,4-Dimethyl-4-pyrrolidinomethyl benzophenone (CAS 898776-51-7)
- Conivaptan Impurity 5 (CAS CATO-C4X-13605)
- Ethyl 2-(3-amino-4-methyl-1h-pyrazol-1-yl)acetate (CAS 1343711-15-8)
- 4,5-DImethyl-2-piperidin-4-yl-1h-benzimidazole dihydrochloride (CAS 1987680-62-5)
- Tirzepatide Impurity 33 (CAS CATO-C4X-324033)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com