Darunavir-d9 CAS 1133378-37-6
| CAS No. | 1133378-37-6 |
| Molecular Formula | - |
| Molecular Weight | 556.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Darunavir-d9 is closely related to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Darunavir-d9 (CAS 1133378-37-6), molecular formula C27H28D9N3O7S and molecular weight 556.72 g/mol, is a CATO reference standard with documented purity and traceability.
Darunavir-d9 (C27H28D9N3O7S) contains deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H28D9N3O7S |
| Molecular Weight | 556.72 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Darunavir Standards
- Darunavir Impurity 36 (CAS CATO-C4X-160636)
- D-Darunavir (CAS 1399859-60-9)
- Darunavir (1R,2R)-Isomer (CAS 1546918-95-9)
- Darunavir Impurity 23 (CAS CATO-C4X-160623)
- Darunavir Impurity 25 (CAS 850141-19-4)
- Darunavir (CAS 206361-99-1)
- Darunavir Impurity 37 (CAS 159005-61-5)
- Darunavir Impurity C85 (CAS 191226-98-9)
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