Darunavir CAS 206361-99-1
| CAS No. | 206361-99-1 |
| Molecular Formula | C27H37N3O7S |
| Molecular Weight | 547.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Darunavir is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Darunavir (CAS 206361-99-1) is a high-purity analytical reference standard with the molecular formula C27H37N3O7S and a molecular weight of 547.66 g/mol.
Darunavir (C27H37N3O7S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Darunavir meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H37N3O7S |
| Molecular Weight | 547.66 g/mol |
| Purity | >98% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Darunavir Standards
- D-Darunavir (CAS 1399859-60-9)
- Darunavir (1R,2R)-Isomer (CAS 1546918-95-9)
- Darunavir Impurity 23 (CAS CATO-C4X-160623)
- Darunavir Impurity 25 (CAS 850141-19-4)
- Darunavir-d9 (CAS 1133378-37-6)
- Darunavir Impurity 36 (CAS CATO-C4X-160636)
- Darunavir Impurity 37 (CAS 159005-61-5)
- Darunavir Impurity C85 (CAS 191226-98-9)
Recommended Standards
- (11bR)-N,N-Bis((S)-1-phenylethyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]di-oxaphosphepin-4-amine (CAS 1021439-60-0)
- (11bR)-N,N-bis((R)-1-phenylethyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 1389329-66-1)
- (11bS)-8,9,10,11,12,13,14,15-Octahydro-N,N-bis[(1R)-1-phenylethyl]-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 479413-76-8)
- (1R,2S)-Darunavir (CAS 1402142-63-5)
- 1-(2-Ethoxyphenyl)-1H-1,2,4-triazole-3,5-diamine (CAS 723725-62-0)
- 3-Aminomethyl-2-Cbz-1,2,3,4-tetrahydro-isoquinoline (CAS 885273-87-0)
- 2-(4-(2H-Indazol-2-yl)phenyl)-N-hydroxypropanamide (CAS 81265-80-7)
- 6,7-Dimethyl-5,12-di(pyridin-4-yl)-5,12-dihydroindolo[3,2-a]carbazole (CAS 1803246-66-3)
- 5-O-Demethyl-4,5-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-22,23-dihydro-28-oxo-Avermectin A1a (CAS 102190-51-2)
- 5-Amino-2-(benzyloxy)benzonitrile (CAS 848134-18-9)
- (2,6-Difluoro-4-pentylphenyl)boronic acid (CAS 125369-58-6)
- 4-Fluoro-7-nitrobenzofurazan (CAS 29270-56-2)
- 3,3-Dimethyl-2-oxobutanal (CAS 4480-47-1)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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