N-[2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea CAS 1135256-66-4
| CAS No. | 1135256-66-4 |
| Molecular Formula | C18H18Cl2N6O |
| Molecular Weight | 405.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-[2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea (CAS 1135256-66-4), a certified reference material (molecular formula C18H18Cl2N6O, MW 405.28 g/mol) for analytical method development and quality control.
N-[2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea (C18H18Cl2N6O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-[2-Amino-6-(3,5-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18Cl2N6O |
| Molecular Weight | 405.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related N Standards
- 3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one (CAS 847445-81-2)
- 6-Amino-4-(3-bromo-4-hydroxy-5-methoxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 667404-58-2)
- 3-(Boc-amino)-4-(4-iodophenyl)butyric Acid (CAS 1824505-64-7)
- 2-Amino-6-{4-[3-(trifluoromethyl)phenoxy]phenyl}pyridine-3,4,5-tricarbonitrile (CAS 478248-02-1)
- ((((((2S)-1-(6-Amino-4H-purin-9(8H)-yl)propan-2-yl)oxy)methyl)(hydroxy)phosphoryl)oxy)methyl isopropyl carbonate (CAS 1841115-98-7)
- 1-Amino-5-hydroxy-4-((2-methoxyphenyl)amino)-8-nitroanthracene-9,10-dione (CAS 71412-38-9)
- 8-Amino-N-(1-(cyclopropanecarbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide (CAS 1449277-10-4)
- 6-Amino-2-(benzylthio)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine 1-oxide (CAS 64570-11-2)
Recommended Standards
- Carboplatin Impurity 12 (CAS 113287-15-3)
- Benzyl 3-(5,8-dichloroimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate (CAS 1419223-17-8)
- N-(2-Bromophenyl)-2-((3-(2-hydroxyphenyl)-1H-1,2,4-triazol-5-yl)thio)acetamide (CAS 336180-29-1)
- PD 089828 (CAS 179343-17-0)
- ethyl 4-methyl-2-oxopiperidine-3-carboxylate (CAS 102943-15-7)
- Tert-butyl 2-(azepan-4-yl)acetate hydrochloride (CAS 1864053-29-1)
- 2-(Chloromethyl)-6-(difluoromethyl)-3-methylpyridine-4-methanol (CAS 1361879-86-8)
- 5-Chloro-2-(trifluoromethoxy)benzyl alcohol (CAS 874821-52-0)
- 3,5-Diethylbenzonitrile (CAS 105905-71-3)
- 4-Chloro-2-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrazine-3-carbaldehyde (CAS 1544841-79-3)
- (R)-3-Isobutylmorpholine (CAS 711014-40-3)
- 2-(5-Methyl-2-nitrophenyl)acetic Acid (CAS 37777-81-4)
- Tert-Butyl 4-Amino-4-Methylazepane-1-Carboxylate (CAS 1541842-26-5)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com