5-Chloro-6-(dimethylamino)-2-methylpyrimidin-4-ol CAS 1135283-12-3
| CAS No. | 1135283-12-3 |
| Molecular Formula | C7H10ClN3O |
| Molecular Weight | 187.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 187.63 g/mol gives 5-Chloro-6-(dimethylamino)-2-methylpyrimidin-4-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 5-Chloro-6-(dimethylamino)-2-methylpyrimidin-4-ol (CAS 1135283-12-3), a certified reference material (molecular formula C7H10ClN3O, MW 187.63 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-6-(dimethylamino)-2-methylpyrimidin-4-ol (C7H10ClN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-6-(dimethylamino)-2-methylpyrimidin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H10ClN3O |
| Molecular Weight | 187.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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- 6-Chloro-N-(2-methoxyethyl)pyridazin-3-amine (CAS 1036569-59-1)
- 1138220-54-8 3-[(6-Chloro-2-pyrazinyl)amino]-1-propanol (CAS 1138220-54-8)
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Recommended Standards
- 4-Chloro-2,5-dimethoxyaniline (CAS 6358-64-1)
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- 6-Chloro-N-(2-methoxyethyl)-2-pyrazinamine (CAS 1220016-30-7)
- 2,4,6-Trichloro-5-iodopyrimidine (CAS 1137576-61-4)
- (2-Amino-3-chloro-5-fluorophenyl)methanol (CAS 2089319-92-4)
- 2-(2-(Pyridin-4-yl)thiazol-4-yl)ethan-1-amine dihydrochloride (CAS 1365836-71-0)
- 2-(4-Chlorophenyl)-1-[(2-chlorophenyl)methanesulfonyl]propan-2-ol (CAS 339276-90-3)
- 1-Chloro-7,7-dimethyl-6,7-dihydro-5H-cyclopenta[d]pyridazine (CAS 2812356-29-7)
- 2-(4-Propylpiperazin-1-yl)ethan-1-amine (CAS 4489-50-3)
- Methyl 2-(4-chlorophenyl)-5-phenyloxazole-4-carboxylate (CAS 1370731-53-5)
- benzyl 4-(5-chloro-1-(2-ethoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1000018-18-7)
- Acotiamide Impurity 36 (CAS CATO-C4X-111436)
- Tau Peptide (401-411)-Lys-Lys trifluoroacetate salt (CAS 2022956-59-6)
Why CATO?
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