Brivudine Impurity 4 CAS CATO-C4X-27584
| CAS No. | CATO-C4X-27584 |
| Molecular Formula | C8H10ClNO2 |
| Molecular Weight | 187.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Brivudine Impurity 4 (CAS CATO-C4X-27584), a pharmacopoeial impurity reference standard (molecular formula C8H10ClNO2, MW 187.62 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C8H10ClNO2, Brivudine Impurity 4 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 187.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Brivudine Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10ClNO2 |
| Molecular Weight | 187.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Brivudine Standards
- Brivudine Impurity 3 (CAS CATO-C4X-27583)
- Brivudine Impurity 2 (CAS 765235-25-4)
- Brivudine Impurity N2 (CAS 69304-49-0)
- Brivudine Impurity 12 (CAS 144301-84-8)
- Brivudine Impurity 13 (CAS 144301-85-9)
- Brivudine Impurity 15 (CAS 113890-35-0)
- Brivudine Impurity 16 (CAS 113890-38-3)
- Brivudine Impurity 10 (CAS 55520-67-7)
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- 5-Cyclopropoxy-N-methyl-2-(trifluoromethyl)benzamide (CAS 1243281-85-7)
- 4,6-Dimethylpyrimidin-2-yl 2,4-dichlorobenzoate (CAS 338421-30-0)
- C-Peptide 2 (rat) (CAS 41594-08-5)
Why CATO?
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