5-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)-3-methoxypyridine CAS 1138443-85-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)-3-methoxypyridine.

5-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)-3-methoxypyridine (CAS 1138443-85-2) is a high-purity analytical reference standard with the molecular formula C13H22BrNO2Si and a molecular weight of 332.31 g/mol.

Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, 5-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)-3-methoxypyridine is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 332.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-2-(((tert-butyldimethylsilyl)oxy)methyl)-3-methoxypyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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