1-Bromo-2-fluoro-4-phenoxybenzene CAS 1138557-58-0
| CAS No. | 1138557-58-0 |
| Molecular Formula | C12H8BrFO |
| Molecular Weight | 267.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 267.09 g/mol gives 1-Bromo-2-fluoro-4-phenoxybenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-Bromo-2-fluoro-4-phenoxybenzene (CAS 1138557-58-0), a certified reference material (molecular formula C12H8BrFO, MW 267.09 g/mol) for analytical method development and quality control.
The molecular framework of 1-Bromo-2-fluoro-4-phenoxybenzene (C12H8BrFO) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8BrFO |
| Molecular Weight | 267.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-Bromo-2-(4-fluorophenoxy)benzene (CAS 1055987-64-8)
- 1-(2-Bromo-4,6-difluorophenyl)thiourea (CAS 1094493-45-4)
- 1-Bromo-4-(1,1,1-trifluoro-2-methylpropan-2-yl)benzene (CAS 1225380-05-1)
- 1-(4-Bromo-3,5-difluorophenyl)thiourea (CAS 1263376-93-7)
- 1-Bromo-3-isopropyl-5-(trifluoromethyl)benzene (CAS 1369928-03-9)
- 1-Bromo-2-(2-fluorophenoxy)benzene (CAS 1445322-62-2)
- 1-Bromo-2-(3-fluorophenoxy)benzene (CAS 884512-15-6)
- 1-Bromo-3-(4-fluorophenoxy)benzene (CAS 50904-38-6)
Recommended Standards
- 1-(Bromomethyl)-4-(1,1,1-trifluoropropan-2-yl)benzene (CAS 1204295-85-1)
- (6-(Benzyloxy)-1H-indol-2-yl)boronic acid (CAS 1218790-97-6)
- 1-(2-Bromopropyl)-4-(trifluoromethyl)benzene (CAS 1021927-60-5)
- Macitentan Impurity 9 (CAS 706811-25-8)
- 4,4'-Sulfonylbis(2,6-dimethylphenol) (CAS 13288-70-5)
- 2,4,6-Tris(4-carboxyphenoxy)-1,3,5-triazine (CAS 118803-83-1)
- 4-(2-Amino-1,3-thiazol-4-yl)benzene-1,3-diol (CAS 90850-44-5)
- Rebamipide Impurity 33 (CAS CATO-C4X-152333)
- 2-(3-(Aminomethyl)pyridin-2-yl)ethan-1-ol (CAS 1373223-52-9)
- 2-(2,4-Bis(tert-pentyl)phenoxy)-N-(3,5-dichloro-4-ethyl-2-hydroxyphenyl)butyramide (CAS 93951-12-3)
- N-(2,4-dinitro-6-(trifluoromethyl)phenyl)-2,3,5,6,8,9,11,12-octahydrobenzo[b][1,4,7,10,13]pentaoxacyclopentadecin-15-amine (CAS 78857-86-0)
- 1-(phenylsulfanyl)cyclopentane-1-carboxylic acid (CAS 57557-65-0)
- 5-bromo-2-chloro-3-fluoro-pyrazine (CAS 1959608-05-9)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
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