4-methyl-5-(trifluoromethyl)thiophene-2-carboxylic acid CAS 1141015-37-3
| CAS No. | 1141015-37-3 |
| Molecular Formula | C7H9F3O2S |
| Molecular Weight | 214.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-methyl-5-(trifluoromethyl)thiophene-2-carboxylic acid (CAS 1141015-37-3), a certified reference material (molecular formula C7H9F3O2S, MW 214.21 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 4-methyl-5-(trifluoromethyl)thiophene-2-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H9F3O2S |
| Molecular Weight | 214.21 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related methyl Standards
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Recommended Standards
- 1-(4-(2,2-Difluoroethoxy)phenyl)propan-1-one (CAS 1178045-63-0)
- (E)-2,3-Difluoro-1-(furan-2-yl)-4-methylhex-2-en-1-one (CAS 108615-80-1)
- 2-(3,4-Difluorophenyl)-2-(ethylamino)acetamide (CAS 1214806-81-1)
- N-(2,2,2-Trifluoroethyl)-1,3-thiazolidine-4-carboxamide (CAS 1078791-19-1)
- 4-(difluoromethyl)-1-(iodomethyl)-2-oxabicyclo[2.1.1]hexane (CAS 2639420-20-3)
- 2-(Aminomethyl)-5-cyano-3-(difluoromethyl)-6-methylpyridine (CAS 1804414-10-5)
- 2-{3a-methyl-1,5-dioxo-1h,2h,3h,3ah,4h,5h-pyrrolo[1,2-a]quinazolin-4-yl}acetic acid (CAS 1000933-03-8)
- (7-Methoxycoumarin-4-yl)acetic acid (CAS 62935-72-2)
- [(1'-Methyl-1,4'-bipiperidin-4-yl)methyl]-(pyridin-4-ylmethyl)amine tetrahydrochloride (CAS 1185296-29-0)
- 2-((4-Amino-5-ethyl-4H-1,2,4-triazol-3-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethan-1-one (CAS 496033-22-8)
- 2-Cyclopropylimidazo[1,2-a]pyridine-7-carboxylic acid (CAS 1341743-58-5)
- 2-(2-(2-Methylfuran-3-carbonyl)hydrazine-1-carbonyl)benzoic acid (CAS 356769-68-1)
- 2-Chloro-N-(2-methoxy-3-dibenzofuranyl)propanamide (CAS 571157-73-8)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
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