1-(4-(2,2-Difluoroethoxy)phenyl)propan-1-one CAS 1178045-63-0
| CAS No. | 1178045-63-0 |
| Molecular Formula | C11H12F2O2 |
| Molecular Weight | 214.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-(2,2-Difluoroethoxy)phenyl)propan-1-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(4-(2,2-Difluoroethoxy)phenyl)propan-1-one (CAS 1178045-63-0), a certified reference material (molecular formula C11H12F2O2, MW 214.21 g/mol) for analytical method development and quality control.
The molecular framework of 1-(4-(2,2-Difluoroethoxy)phenyl)propan-1-one (C11H12F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(4-(2,2-Difluoroethoxy)phenyl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12F2O2 |
| Molecular Weight | 214.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Difluoroethoxy Standards
- N-(4-(2,2-difluoroethoxy)benzyl)ethanamine (CAS 1178035-49-8)
- N-(2-(2,2-difluoroethoxy)benzyl)ethanamine (CAS 1183458-43-6)
- 1-[4-(2,2-Difluoroethoxy)phenyl]propan-1-amine (CAS 1184222-88-5)
- N-(3-(2,2-difluoroethoxy)benzyl)ethanamine (CAS 1184680-66-7)
- 4-(2,2-Difluoroethoxy)-3-methoxybenzaldehyde (CAS 1179127-75-3)
- 2-(2,2-Difluoroethoxy)-3-methoxybenzaldehyde (CAS 1184531-70-1)
- 4-(2,2-Difluoroethoxy)-3-methylbenzoic acid (CAS 1373864-75-5)
- 2-[4-(2,2-difluoroethoxy)phenyl]acetic acid (CAS 937602-66-9)
Recommended Standards
- 4-methyl-5-(trifluoromethyl)thiophene-2-carboxylic acid (CAS 1141015-37-3)
- 2-(3,4-Difluorophenyl)-2-(ethylamino)acetamide (CAS 1214806-81-1)
- 2-[5-(trifluoromethyl)-2-thienyl]acetic acid (CAS 1095560-61-4)
- 2,5-Difluoro-isobuylbenzoate (CAS 1227269-26-2)
- Hept-6-enal (CAS 17206-61-0)
- (4-Chlorophenyl)methylphosphonic acid (CAS 39225-05-3)
- Prop-2-yn-1-yl 3-chloro-4-((4-chlorobenzyl)oxy)benzoate (CAS 1706429-00-6)
- 2-(2-((4-Methylpentan-2-yl)amino)ethoxy)ethan-1-ol (CAS 1038247-08-3)
- Milnacipran Impurity 22 (CAS 2254103-64-3)
- 2,4-Di-tert-butyl-5-nitroaniline (CAS 342045-18-5)
- 2-[Bis[3,5-bis(trifluoromethyl)phenyl]phosphino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]benzamide (CAS 2407524-35-8)
- 1-(2-Cyclopropyl-6-phenylpyrimidin-4-yl)-1H-imidazole-4-carboxylic acid (CAS 1707735-60-1)
- (2-(4-Methylpiperazin-1-yl)pyridin-3-yl)methanol (CAS 1225920-65-9)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
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