2-Bromo-5-iodopyridin-3-ol CAS 1142191-52-3
| CAS No. | 1142191-52-3 |
| Molecular Formula | C5H9BrINO |
| Molecular Weight | 305.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-iodopyridin-3-ol.
2-Bromo-5-iodopyridin-3-ol (CAS 1142191-52-3), molecular formula C5H9BrINO and molecular weight 305.94 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-5-iodopyridin-3-ol (C5H9BrINO) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-5-iodopyridin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9BrINO |
| Molecular Weight | 305.94 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br/I-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-bromo-3-iodopyrazin-2-amine (CAS 1062608-42-7)
- 5-Bromo-2-iodopyridin-3-ol (CAS 188057-49-0)
- 5-Bromo-4,6-dichloro-2-(methylsulfonyl)pyrimidine (CAS 98028-01-4)
- 2-Bromo-1-(2-bromo-4,6-dimethylphenyl)ethan-1-one (CAS 1246471-30-6)
- 3-Bromo-4-(2-bromophenyl)butan-2-one (CAS 1247825-43-9)
- 4-Bromo-3-(2,4-dichlorophenyl)-1-methyl-1H-pyrazole (CAS 133112-51-3)
- 7-bromo-5-(2-bromoethyl)-2,3-dihydroBenzofuran (CAS 1391080-45-7)
- 7-Bromo-2,4-dichloro-6-ethylquinazoline (CAS 2771459-73-3)
Recommended Standards
- 2,5-Dichloro-4-(difluoromethoxy)benzyl bromide (CAS 1807184-76-4)
- 3,6-Dibromo-5-methoxy-1H-pyrrolo[3,2-b]pyridine (CAS 1000341-07-0)
- 2,3-Dichloro-5-(difluoromethoxy)benzyl bromide (CAS 1806353-20-7)
- 4,5-Dibromo-N-(prop-2-yn-1-yl)-1H-pyrrole-2-carboxamide (CAS 1006055-08-8)
- (3-Amino-1H-1,2,4-triazol-5-yl)methanol compound with 2-hydroxyacetic acid (CAS 63870-39-3)
- 6-Iodohexan-1-amine hydrochloride (CAS 98275-58-2)
- 4-Chloro-2-phenyl-6-[(phenylsulfanyl)methyl]pyrimidine (CAS 339103-91-2)
- (1-(3-Aminopyridin-2-yl)piperidin-2-yl)methanol (CAS 1283917-21-4)
- Menaquinone 9 (CAS 523-39-7)
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-8-(trifluoromethyl)quinoline (CAS 2235386-18-0)
- tert-Butyl 2-cyanonicotinate (CAS 114429-07-1)
- (S)-2-Amino-N-isopropyl-3-methyl-N-(2-oxo-2-(thiazol-2-yl)ethyl)butanamide (CAS 1354010-79-9)
- N-Benzyl-2-oxo-1,2-dihydropyridine-4-carboxamide (CAS 1018046-16-6)
- Semaglutide Impurity 144 (CAS 394210-59-4)
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