5-Bromo-2-iodopyridin-3-ol CAS 188057-49-0
| CAS No. | 188057-49-0 |
| Molecular Formula | C5H9BrINO |
| Molecular Weight | 305.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Bromo-2-iodopyridin-3-ol (CAS 188057-49-0), a certified reference material (molecular formula C5H9BrINO, MW 305.94 g/mol) for analytical method development and quality control.
The molecular framework of 5-Bromo-2-iodopyridin-3-ol (C5H9BrINO) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H9BrINO |
| Molecular Weight | 305.94 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | Br/I-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2-amino-3-(5-bromo-2-methoxyphenyl)propanoic acid hydrochloride (CAS 1354950-21-2)
- URANYL NITRATE HEXAHYDRATE, ACS (CAS 13520-83-7)
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- 1-((((9h-Fluoren-9-yl)methoxy)carbonyl)amino)-4-ethylcyclohexane-1-carboxylic acid (CAS 1339220-30-2)
- 1-Bromo-3,4,5-trimethoxybenzene 1-bromo-3,4,5-trimethoxybenzene 3,4,5-trimethoxybromobenzene 2675-79-8 3,4,5-triemethoxyphenylbromide 3,4,5-trimethoxybromoben 3,4,5-trimethoxybromobenzene 5-bromo-1,2,3-trimethoxybenzene 5-bromo-1,2,3-trimethoxybenzene98% bromotrimethoxybenzene (CAS 2675-79-8)
- 2-Chloro-4-(naphthalen-1-yl)quinazoline (CAS 1413376-86-9)
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