Flunarizine impurity 57 CAS 114374-24-2
| CAS No. | 114374-24-2 |
| Molecular Formula | C24H24F2N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Flunarizine impurity 57 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Flunarizine impurity 57 (CAS 114374-24-2) is a certified pharmaceutical impurity reference standard with the molecular formula C24H24F2N2HCl and a molecular weight of 414.92 g/mol.
Flunarizine impurity 57 (C24H24F2N2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Flunarizine impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H24F2N2 2*HCl |
| Molecular Weight | 414.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Flunarizine Standards
- Flunarizine impurity 43 (CAS 1133842-25-7)
- Flunarizine Impurity 59 (CAS 114312-65-1)
- Flunarizine Impurity N1 (CAS 123375-94-0)
- Flunarizine Impurity N1 HCl (CAS 123375-94-0(free base))
- Flunarizine impurity 46 (CAS 1368426-98-5(free base))
- Flunarizine Impurity 32 (CAS 141528-78-1)
- Flunarizine Impurity 26 (CAS 144917-53-3)
- Flunarizine impurity 47 (CAS 148728-47-6)
Recommended Standards
- Vancomycin impurity 26 (CAS CATO-C4X-177526)
- Vazegepant impurity 37 (CAS CATO-C4X-320037)
- Fezolinetant Impurity 9 (CAS 1629229-47-5)
- 5-Oxa-9-azaspiro[3.5]nonane (CAS 2137579-91-8)
- (1R,2R)-1-Amino-1-phenylpropan-2-ol hydrochloride (CAS 255060-27-6)
- 3,4,6-Trimethylpyrazolo[1,5-a]pyrimidin-7(4H)-one (CAS 4081-82-7)
- Paroxetine EP Impurity I (CAS 125224-43-3)
- 1-(2-(1h-1,2,4-Triazol-1-yl)phenyl)ethan-1-one (CAS 19542-23-5)
- (5S)-5-Benzylmorpholin-3-one (CAS 101250-48-0)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com