Docetaxel Impurity 47 CAS 1144034-42-3
| CAS No. | 1144034-42-3 |
| Molecular Formula | C40H47NO13 |
| Molecular Weight | 749.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 749.80 g/mol gives Docetaxel Impurity 47 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Docetaxel Impurity 47 (CAS 1144034-42-3) is a certified pharmaceutical impurity reference standard with the molecular formula C40H47NO13 and a molecular weight of 749.80 g/mol.
Docetaxel Impurity 47 (C40H47NO13) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Docetaxel Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H47NO13 |
| Molecular Weight | 749.80 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
Related Docetaxel Standards
- Docetaxel Impurity 28(N-Formyl impurity) (CAS CATO-C4X-161928)
- Docetaxel Impurity 55 (CAS 173101-59-2)
- Docetaxel Impurity 54 (CAS 173101-47-8)
- Docetaxel Impurity 43 (CAS 114915-19-4)
- Docetaxel Impurity 44 (CAS CATO-C4X-161944)
- Docetaxel EP Impurity A (CAS 1887057-05-7)
- Docetaxel Impurity 68 (CAS 133524-69-3)
- Docetaxel EP Impurity B (CAS 167074-97-7)
Recommended Standards
- 4-Desacetyl-2-debenzoyl-[2,4]-oxol Paclitaxel (CAS 159500-49-9)
- 1-(4-Formylphenyl)-1-oxo-5,8,11,14,17,20,23,26,29,32,35,38-dodecaoxa-2-azahentetracontan-41-oic acid (CAS 1415408-70-6)
- Ketoconazole EP Impurity B (and enantiomer) (CAS CATO-C4X-14722)
- Posaconazole Impurity 170 (CAS CATO-C4X-1208170)
- Brivaracetam Impurity 3 (CAS 357336-99-3)
- Edoxaban Impurity 74 (CAS 1210348-21-2)
- Nevirapine EP Impurity C (CAS 287980-85-2)
- 6-Oxo-Estradiol-17-Valerate (CAS 1313382-51-2)
- (S)-1-((S)-3-Methyl-2-(methylamino)butyl)pyrrolidin-3-oldihydrochloride (CAS 1217852-55-5)
- 2-(Carboxy(hydroxy)methyl)-5-methylbenzo[d]oxazole (CAS 1521909-59-0)
- 4-(2,4-Dichlorophenyl)-2-(4-methoxyphenoxy)-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 341965-00-2)
- 4-(3-Amino-phenyl)-thiazol-2-ylamine (CAS 610279-47-5)
- 2-(Cyclopentylmethoxy)-4-methylaniline (CAS 640767-93-7)
- Acetyl-(Leu28ยท31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
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