3-Chloro-5-fluorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate CAS 1144036-48-5
| CAS No. | 1144036-48-5 |
| Molecular Formula | C22H21ClFN3O5 |
| Molecular Weight | 461.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Chloro-5-fluorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (C22H21ClFN3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Chloro-5-fluorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144036-48-5) is a high-purity analytical reference standard with the molecular formula C22H21ClFN3O5 and a molecular weight of 461.87 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chloro-5-fluorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H21ClFN3O5 |
| Molecular Weight | 461.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(4-methyl-2-phenylpyrimidin-5-yl)methanone (CAS 338399-42-1)
- 4-(4-(2-((2-Chloro-4-(trifluoromethyl)phenyl)amino)ethyl)-5-methyl-4H-1,2,4-triazol-3-yl)-1-phenyl-1H-pyrazol-5-amine (CAS 957040-55-0)
- N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine (CAS 267243-64-1)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(1,2-dihydronaphtho[2,1-b]furan-2-yl)methanone (CAS 478064-60-7)
- 5-Chloro-N-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide (CAS 1235406-69-5)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((dimethylamino)methylene)-4-(phenylsulfonyl)butanamide (CAS 338420-80-7)
- 4-Chloro-3-(difluoromethoxy)-1-trityl-1H-pyrazolo[4,3-c]pyridine (CAS 2756656-96-7)
- 5''-Chloro-N-((5,6-dimethoxypyridin-2-yl)methyl)-[2,2':5',3''-terpyridine]-3'-carboxamide (CAS 1207253-08-4)
Recommended Standards
- Methyl 3-(2-chlorophenyl)-5-(1-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole-4-carboxylate (CAS 318949-18-7)
- (3Z)-3-{[(3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-1-(pyrimidin-2-yl)pyrrolidin-2-one (CAS 338954-33-9)
- Chlorotricarbonyl(2,2'-bipyridine)rhenium(I) (CAS 55658-96-3)
- 3-((4-Bromophenyl)thio)-3-(4-chlorophenyl)-1-(4-methoxyphenyl)propan-1-one (CAS 329779-48-8)
- Ethyl 2-benzylthiazole-4-carboxylate (CAS 83553-49-5)
- (6,7-Diethoxy-3-methyl-5-nitrobenzofuran-2-yl)(morpholino)methanone (CAS 40713-22-2)
- NH-bis-PEG5 (CAS 63721-06-2)
- N-(1-(4-Isobutylphenyl)ethyl)-2-(methylthio)nicotinamide (CAS 795294-92-7)
- 2,4-Dimethylquinolin-8-amine (CAS 3393-70-2)
- ((3R,4R)-4-amino-1-benzylpiperidin-3-yl)methanol (CAS 1821774-60-0)
- (8-Methylquinolin-3-yl)boronic acid (CAS 1370040-72-4)
- 8-Bromo-6-fluoro-2,7-dimethylquinoline (CAS 1420793-57-2)
- 4,6-Dimethyl-2-oxo-1,2-dihydropyridine-3-carboximidamide (CAS 885967-09-9)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
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