N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine CAS 267243-64-1
| CAS No. | 267243-64-1 |
| Molecular Formula | C21H21ClFN5O4 |
| Molecular Weight | 461.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine (CAS 267243-64-1), molecular formula C21H21ClFN5O4 and molecular weight 461.87 g/mol, is a CATO reference standard with documented purity and traceability.
N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine (C21H21ClFN5O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C21H21ClFN5O4 |
| Molecular Weight | 461.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
- MK-2048 (CAS 869901-69-9)
- Clindamycin Impurity 82 (CAS CATO-C4X-134182)
- Chlorotricarbonyl(2,2'-bipyridine)rhenium(I) (CAS 55658-96-3)
- Clindamycin Impurity 84 (CAS CATO-C4X-134184)
- 4-((5-Oxo-4,5-dihydro-1,2,4-triazin-3-yl)amino)benzoic acid (CAS 878733-17-6)
- tert-Butyl 2-(quinolin-6-yl)pyrrolidine-1-carboxylate (CAS 1355225-80-7)
- (E)-(3-iodoprop-1-en-1-yl)benzene (CAS 82859-39-0)
- Shatavarin IV (CAS 84633-34-1)
- (S)-4-Benzyl-3-((R)-3-cyclopentyl-3-hydroxypent-4-ynoyl)oxazolidin-2-one (CAS 1508318-85-1)
- Ethyl 5-formyl-1-methyl-1H-imidazole-4-carboxylate (CAS 2106384-57-8)
- 2-Aminoperimidine hydrobromide hydrate (CAS 313223-13-1)
- Methyl 5-chloro-2-methoxy-4-(methylamino)benzoate (CAS 78775-33-4)
- Isoprenaline Impurity 44 (CAS CATO-C4X-277544)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com