1-(3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidine-3-carboxylic acid CAS 1144436-95-2
| CAS No. | 1144436-95-2 |
| Molecular Formula | C12H12F3N5O2 |
| Molecular Weight | 315.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1-(3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
1-(3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidine-3-carboxylic acid (CAS 1144436-95-2), molecular formula C12H12F3N5O2 and molecular weight 315.25 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidine-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 315.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H12F3N5O2 |
| Molecular Weight | 315.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Trifluoromethyl Standards
- 1-(5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidine-4-carboxylic acid (CAS 1707594-13-5)
- 1-(5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidine-3-carboxylic acid (CAS 1707671-77-9)
- 1-(3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidine-4-carboxylic acid (CAS 923776-21-0)
- 4-{[3-(trifluoromethyl)quinoxalin-2-yl]oxy}benzonitrile (CAS 338773-68-5)
- 3-[3-(Trifluoromethyl)benzamido]thiophene-2-carboxylic acid (CAS 866150-49-4)
- N'-[6-(Trifluoromethyl)pyridine-3-carbonyl]cyclohexanecarbohydrazide (CAS 1092346-05-8)
- 2-((3-(Trifluoromethyl)phenyl)carbamoyl)cyclohexane-1-carboxylic acid (CAS 304674-19-9)
- 2-(6-Phenyl-4-(trifluoromethyl)pyridin-2-yl)phenol (CAS 710354-96-4)
Recommended Standards
- 1076199-55-7 5-Bromo Brassinin N-[(5-Bromo-1H-isoindol-3-yl)methyl]carbamodithioic Acid Methyl Ester (CAS 1076199-55-7)
- 1-((8-Bromooctyl)oxy)-4-methoxybenzene (CAS 125878-82-2)
- Isopropyl 5-oxo-1-(3-(trifluoromethyl)phenyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000574-65-1)
- Ethyl 5-amino-1-(4-(trifluoromethoxy)phenyl)-1H-pyrazole-3-carboxylate (CAS 1369271-77-1)
- 8-Fluoroimidazo[1,2-a]pyridin-3-amine (CAS 1427361-55-4)
- 2-Amino-5-bromo-6-isopropylpyrimidin-4(3H)-one (CAS 95525-00-1)
- 2-[(4-aminophenyl)methyl]butanoic acid (CAS 103893-69-2)
- 7-Amino-2-ethyl-3,4-dihydroisoquinolin-1(2h)-one (CAS 1267025-23-9)
- (4-(2-(Cyclopentylamino)ethoxy)-3-fluorophenyl)boronic acid (CAS 1704096-02-5)
- 4-(2-Bromo-6-fluorobenzyl)morpholine, 97% (CAS 1345472-12-9)
- 2-(3,4-Dichloro-1-methyl-1H-pyrazol-5-yl)-2-methyl-N-(p-tolyl)hydrazine-1-carboxamide (CAS 318284-29-6)
- 3,4,5,6-Tetrachloro-2-cyanobenzoic acid ammoniumsalt (CAS 34643-39-5)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-one O-(4-chlorobenzyl) oxime (CAS 250714-04-6)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com