Imatinib-d3 CAS 1144803-18-1
| CAS No. | 1144803-18-1 |
| Molecular Formula | - |
| Molecular Weight | 496.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Imatinib-d3 (CAS 1144803-18-1) is a high-purity analytical reference standard with the molecular formula C29H28D3N7O and a molecular weight of 496.62 g/mol.
Structurally, Imatinib-d3 (C29H28D3N7O) contains deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 19.5, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 496.62 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Imatinib-d3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H28D3N7O |
| Molecular Weight | 496.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 7 |
Related Imatinib Standards
- Imatinib-d3 (N-methyl-d3) (CAS 1134803-18-1)
- Imatinib Para-diaminomethylbenzene Impurity-d3 (CAS 1246819-27-1)
- Imatinib Impurity 10 (CAS 1026753-54-7)
- Imatinib (CAS 152459-95-5)
- Imatinib meta-MPM Impurity (CAS 1246819-59-9)
- Imatinib-d8 (CAS 1092942-82-9)
- Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) (CAS 1185103-28-9)
- 6-Methyl Imatinib (CAS 1032314-85-4)
Recommended Standards
- Propargyl-PEG4-S-PEG4-acid (CAS 2055041-20-6)
- Mirabegron N-t-BOC Impurity (CAS 1329485-55-3)
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- (2E)-2-{4-[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl]-1,3-thiazol-2-yl}-3-[1-(2-methylpropyl)-1,2,3,4-tetrahydroquinolin-6-yl]prop-2-enenitrile (CAS 866019-86-5)
- 3-Pentanone-2,2,4,4-d4 (CAS 6400-97-1)
- 2-((2-Bromopyridin-3-yl)oxy)-N-(tert-butyl)acetamide (CAS 1376326-48-5)
- N-(1-Methylpiperidin-4-yl)nicotinamide (CAS 830339-06-5)
- 2-(Methylthio)benzo[d]oxazole-5-methanol (CAS 1804497-80-0)
- 5-Cyclopropoxy-N,N-dimethyl-4-(trifluoromethyl)nicotinamide (CAS 1243440-58-5)
- 5-(aZepan-1-yl)-2-chloroaniline (CAS 1175962-38-5)
- 3-(4-Fluoro-2-methylphenyl)-3-hydroxypropanenitrile (CAS 1510168-67-8)
- tert-Butyl 3-[(piperidin-4-yl)methyl]azetidine-1-carboxylate (CAS 1781986-49-9)
- Lifitegrast Impurity 146 (CAS CATO-C4X-2409146)
- Peptide Impurity 13 (CAS CATO-CPTD788813)
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