Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) CAS 1185103-28-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.1185103-28-9
Molecular Formula-
Molecular Weight487.63 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) CAS 1185103-28-9 chemical structure

Description

Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) (CAS 1185103-28-9) is a certified pharmaceutical impurity reference standard with the molecular formula C28H21D8N7O and a molecular weight of 487.63 g/mol.

Owing to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 487.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC28H21D8N7O
Molecular Weight487.63 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)22.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms7

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