2-(2-Chloro-5-nitrophenyl)-5-methyl-1H-1,2,4-triazol-3(2H)-one CAS 114499-57-9
| CAS No. | 114499-57-9 |
| Molecular Formula | C9H7ClN4O3 |
| Molecular Weight | 254.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(2-Chloro-5-nitrophenyl)-5-methyl-1H-1,2,4-triazol-3(2H)-one (CAS 114499-57-9) is a high-purity analytical reference standard with the molecular formula C9H7ClN4O3 and a molecular weight of 254.63 g/mol.
2-(2-Chloro-5-nitrophenyl)-5-methyl-1H-1,2,4-triazol-3(2H)-one (C9H7ClN4O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-(2-Chloro-5-nitrophenyl)-5-methyl-1H-1,2,4-triazol-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7ClN4O3 |
| Molecular Weight | 254.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- Methyl 2-(3-chloro-2-nitrophenyl)-2-cyanoacetate (CAS 127500-23-6)
- Ethyl 2-(8-chloro-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-2-oxoacetate (CAS 1315365-24-2)
- 2-Chloro-4-isopropoxy-1-(trifluoromethoxy)benzene (CAS 1395039-10-7)
- 2-(5-Chloro-2-methoxyphenyl)-1,1,1-trifluoropropan-2-ol (CAS 1402004-22-1)
- 1-(5-Chloro-1-methyl-6-oxo-1,6-dihydropyridazin-4-yl)-1H-pyrazole-3-carboxylic acid (CAS 1707735-62-3)
- 1-(5-Chloro-1-methyl-6-oxo-1,6-dihydropyridazin-4-yl)-1H-imidazole-4-carboxylic acid (CAS 1710845-90-1)
- 1-chloro-3-propoxy-5-(trifluoromethoxy)benzene (CAS 1881289-52-6)
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Recommended Standards
- 2-[1-(6-chloropyridazin-3-yl)-5-oxo-4,5-dihydro-1h-pyrazol-3-yl]acetic acid (CAS 1094331-75-5)
- 6-Chloro-7-methoxy-2-oxo-2H-chromene-3-carboxylic acid (CAS 704882-50-8)
- 6-chloro-4-(difluoromethyl)-8-oxa-3,5-diazatricyclo[7.4.0.0²,⁷]trideca-1(13),2,4,6,9,11-hexaene (CAS 2866218-02-0)
- 4-Amino-2-fluoro-5-nitrobenzenesulfonyl chloride (CAS 2550442-23-2)
- 2-(4,5-Dichloro-1H-imidazol-1-yl)acetohydrazide (CAS 175137-68-5)
- 6-(Difluoromethyl)-4-(trifluoromethyl)pyridin-2(1H)-one (CAS 1806776-43-1)
- IMidodicarbonic acid, 2-(3-nitro-2-pyridinyl)-, 1,3-bis(1,1-dimethylethyl) ester (CAS 1044758-23-7)
- 4-(3,5-Dichlorophenyl)oxazolidin-2-one (CAS 1496336-32-3)
- N-(2-(1-Methyl-1H-indol-3-yl)ethyl)-2-(trifluoromethyl)benzamide (CAS 920537-42-4)
- 2-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole (CAS 383142-25-4)
- 1-(2H-1,2,3-Triazol-4-yl)ethanone (CAS 6595-45-5)
- Avatrombopag Impurity 59 (CAS 2948773-23-5)
- Gimeracil Impurity 17 (CAS 84719-31-3)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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