4-Chloro-5-methoxy-2-(3-nitrophenyl)pyrimidine CAS 1147979-38-1
| CAS No. | 1147979-38-1 |
| Molecular Formula | C11H8ClN3O3 |
| Molecular Weight | 265.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-5-methoxy-2-(3-nitrophenyl)pyrimidine.
4-Chloro-5-methoxy-2-(3-nitrophenyl)pyrimidine (CAS 1147979-38-1), molecular formula C11H8ClN3O3 and molecular weight 265.65 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H8ClN3O3, 4-Chloro-5-methoxy-2-(3-nitrophenyl)pyrimidine contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 265.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8ClN3O3 |
| Molecular Weight | 265.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-(2-Chloro-5-nitrophenyl)-3-cyclopropyl-1,2,4-oxadiazole (CAS 1165931-67-8)
- 5-(5-Chloro-4-methyl-2-nitrophenyl)furan-2-carbaldehyde (CAS 1211027-21-2)
- 5-Chloro-6-[(3,4-difluorophenyl)amino]pyridine-3-carbonitrile (CAS 1240526-18-4)
- 5-Chloro-4-(4-methyl-3-nitrophenyl)pyridazin-3(2h)-one (CAS 1245646-50-7)
- 2-(2-Chloro-6-fluorophenyl)-7-fluoro-2H-pyrazolo[4,3-c]pyridine (CAS 1378040-67-5)
- (4-Chloro-3-nitrophenyl)(1-methyl-1H-imidazol-2-yl)methanone (CAS 32902-22-0)
- 1-(5-(2-Chloro-4-nitrophenyl)furan-2-yl)ethan-1-one (CAS 657405-45-3)
- 1-(5-(4-Chloro-2-nitrophenyl)furan-2-yl)ethan-1-one (CAS 886502-68-7)
Recommended Standards
- 4-(Benzo[d][1,3]dioxol-5-yloxy)-6-chloropyrimidin-5-amine (CAS 1090892-67-3)
- 5-Carbamoyl-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylic acid (CAS 103053-08-3)
- 2-(Trifluoromethyl)benzo[d]thiazole-6-carbonyl chloride (CAS 55439-74-2)
- 2-(Chloromethyl)-5-(difluoromethyl)-4-methoxypyridine-3-acetic acid (CAS 1806990-51-1)
- 5-(Trifluoromethyl)-2,3-dihydro-1H-inden-4-amine (CAS 2771332-91-1)
- (4-Acetylphenyl)phenylmethane (CAS 782-92-3)
- n-((Tetrahydrofuran-2-yl)methyl)-5-(trifluoromethyl)pyridin-2-amine (CAS 838902-19-5)
- Benzyl (R)-4-formyl-2,2-dimethyloxazolidine-3-carboxylate (CAS 133464-37-6)
- 2-[(4-Biphenylyl)(4-bromophenyl)amino]-9,9-dimethylfluorene (CAS 1246562-40-2)
- Perfluoro-2-propoxypropanoic acid chloride (CAS 72848-57-8)
- 1-(Bromomethyl)-4-ethynylbenzene (CAS 351002-91-0)
- 4,5-Dimethylpicolinic acid (CAS 802256-42-4)
- Methyl 4-(2-aminoethyl)piperazine-1-carboxylate (CAS 1095017-29-0)
- Tirzepatide Impurity 57 (CAS CATO-C4X-324057)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com