Methyl 2-amino-4-(3-chlorophenyl)pyrimidine-5-carboxylate CAS 1150163-89-5
| CAS No. | 1150163-89-5 |
| Molecular Formula | C12H10ClN3O2 |
| Molecular Weight | 263.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 2-amino-4-(3-chlorophenyl)pyrimidine-5-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Methyl 2-amino-4-(3-chlorophenyl)pyrimidine-5-carboxylate (CAS 1150163-89-5), a certified reference material (molecular formula C12H10ClN3O2, MW 263.68 g/mol) for analytical method development and quality control.
Structurally, Methyl 2-amino-4-(3-chlorophenyl)pyrimidine-5-carboxylate (C12H10ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 263.68 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2-amino-4-(3-chlorophenyl)pyrimidine-5-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN3O2 |
| Molecular Weight | 263.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- Methyl 2-amino-4-(4-chlorophenyl)pyrimidine-5-carboxylate (CAS 1133115-56-6)
- Methyl 2-amino-4-(2-chlorophenyl)pyrimidine-5-carboxylate (CAS 1133115-68-0)
- 2-Amino-5-(4-chlorophenoxy)benzoic acid (CAS 117297-52-6)
- 3-Amino-4-(4-chlorophenoxy)benzoic acid (CAS 1178359-99-3)
- 3-Amino-5-chloro-2-hydroxyphenyl benzoate (CAS 1221791-82-7)
- (4-Amino-5-chloro-2,3-dihydrobenzofuran-7-yl)(1H-imidazol-1-yl)methanone (CAS 196308-41-5)
- 6-amino-5-(2-chloroacetyl)-1-(2-methoxyethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 941117-65-3)
- 2-Amino-9-chloro-4H-[1,3]thiazino[5,6-c]quinolin-4-one (CAS 1015560-19-6)
Recommended Standards
- 2-chloro-N-[(5-methylfuran-2-yl)methyl]-7H-purin-6-amine (CAS 1133758-66-3)
- 4-Chloro-6-ethyl-2-(4-nitrophenyl)pyrimidine (CAS 1153297-96-1)
- 1-(2-chlorophenyl)-5-cyclopropyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 1154372-57-2)
- 1-Allyl-7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 105946-14-3)
- 5-Bromo-N-(4-bromobenzo[d]thiazol-2-yl)thiophene-2-carboxamide (CAS 892857-21-5)
- 1-(2-Bromo-4-methylphenyl)-1H-pyrrole-2-carboxylic acid (CAS 952958-79-1)
- N-Methylmorpholine-4-carboxamide (CAS 126401-65-8)
- (S)-(+)-4-(2,3-Epoxypropoxy)carbazole (CAS 95093-95-1)
- SC75741 (CAS 913822-46-5)
- 1-O-Benzyloxycarbonyl-4-O,6-O-ethylidene-β-D-glucopyranose (CAS 35901-25-8)
- 3,4-Dibromo-1,1'-biphenyl (CAS 60108-72-7)
- 3-aminopropane-1-thiol (CAS 462-47-5)
- Atogepant Impurity 31 (CAS 1375471-11-6)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
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