Methyl 1-(5-chloro-3-fluoropyridin-2-yl)-5-cyclopropylpyrazole-4-carboxylate CAS 1150164-42-3
| CAS No. | 1150164-42-3 |
| Molecular Formula | C13H11ClFN3O2 |
| Molecular Weight | 295.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 295.70 g/mol gives Methyl 1-(5-chloro-3-fluoropyridin-2-yl)-5-cyclopropylpyrazole-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 1-(5-chloro-3-fluoropyridin-2-yl)-5-cyclopropylpyrazole-4-carboxylate (CAS 1150164-42-3) is a high-purity analytical reference standard with the molecular formula C13H11ClFN3O2 and a molecular weight of 295.70 g/mol.
Based on its molecular formula C13H11ClFN3O2, Methyl 1-(5-chloro-3-fluoropyridin-2-yl)-5-cyclopropylpyrazole-4-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 295.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 1-(5-chloro-3-fluoropyridin-2-yl)-5-cyclopropylpyrazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11ClFN3O2 |
| Molecular Weight | 295.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 2-Chloro-n-[5-(5-cyclopropyl-1h-1,2,3,4-tetrazol-1-yl)-2-fluorophenyl]acetamide (CAS 1394041-32-7)
- (E)-[(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)methylidene]amino 4-fluorobenzoate (CAS 477709-09-4)
- 2-[(5-Chloro-1,2,3-thiadiazol-4-yl)methoxy]-2,3-dihydro-1H-isoindole-1,3-dione (CAS 338761-46-9)
- 2-(4-Chloro-2'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetonitrile (CAS 1261599-40-9)
- 1-Chloro-2-fluoro-3-(2-methoxy-4-nitrobenzyl)benzene (CAS 1427501-84-5)
- 1797116-69-8 5-Chloro-N-(5-methoxy-2-hydroxyphenyl)-2-fluoro-benzamide (CAS 1797116-69-8)
- (2-Chloro-4-(trifluoromethyl)phenyl)-D-valine (CAS 76769-07-8)
- (2S)-2-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-3-methylbutanoic acid (CAS 74971-63-4)
Recommended Standards
- Moxifloxacin impurity 175 (CAS 104599-90-8)
- tert-Butyl 2-(6-chloro-3-(trifluoromethyl)pyridin-2-yl)acetate (CAS 748153-46-0)
- tert-Butyl (2-chloro-3-(trifluoromethyl)phenyl)carbamate (CAS 908123-86-4)
- Methyl 1-(2-chloro-6-fluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 400086-05-7)
- 4-Hydroxy-4-(thiazol-2-yl)piperidine-1-carboxylic acid tert-butyl ester (CAS 942185-02-6)
- 6-bromo-1-benzothiophene-3-carboxylic acid (CAS 19075-61-7)
- 2-(5-Methyl-1h-1,2,3,4-tetrazol-1-yl)-3-phenylprop-2-enoic acid (CAS 1738-50-7)
- 6-fluoro-7-nitro-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS 1160591-69-4)
- (2-Chloro-4-fluorophenyl)methanesulfonyl chloride (CAS 541528-45-4)
- 4-Hydroxycyclohexane-1-carboxamide (CAS 1221724-30-6)
- 4-Amino-N-benzyl-N-methylbenzene-1-sulfonamide (CAS 108622-87-3)
- Methyl 2-carbamothioyl-5-fluoroisonicotinate (CAS 2769699-25-2)
- 1-Iodo-2-methoxy-3-nitrobenzene (CAS 211943-70-3)
- 1-His-N-a-ethylidene Semaglutide (CAS CATO-C4X-2226252)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com