4-Amino-7-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide CAS 115044-80-9
| CAS No. | 115044-80-9 |
| Molecular Formula | C12H13N5O3 |
| Molecular Weight | 275.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Amino-7-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Amino-7-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (CAS 115044-80-9) is a high-purity analytical reference standard with the molecular formula C12H13N5O3 and a molecular weight of 275.26 g/mol.
The molecular framework of 4-Amino-7-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (C12H13N5O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Amino-7-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13N5O3 |
| Molecular Weight | 275.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 5 |
Related Amino Standards
- 2-((4-Amino-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methoxy)ethyl acetate (CAS 120386-04-1)
- 2-(4-Amino-3-benzyl-2,6-dioxo-3,6-dihydropyrimidin-1(2h)-yl)acetic acid (CAS 1239788-14-7)
- Methyl 5-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazole-4-carboxylate (CAS 1416344-35-8)
- 4-Amino-7-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (CAS 15676-19-4)
- Ethyl 2-amino-5-(4-nitrophenyl)-1H-pyrrole-3-carboxylate (CAS 187724-88-5)
- 3-Amino-3-(5-(4-nitrophenyl)furan-2-yl)propanamide (CAS 771522-36-2)
- 4-[5-Amino-4-(ethoxycarbonyl)-1h-pyrazol-1-yl]benzoic acid (CAS 926203-48-7)
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Recommended Standards
- 3-ethyl-8-methyl-4-oxo-1,4-dihydroquinoline-3,8-dicarboxylate (CAS 111185-66-1)
- 1-(2-Methoxy-4-nitrophenyl)-3,5-dimethyl-1H-pyrazole-4-carbaldehyde (CAS 1159697-62-7)
- 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-5-ethyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1097065-24-1)
- 2-(2,3-Dimethoxyphenoxy)nicotinic acid (CAS 1160264-58-3)
- 2-Bromo-6-(chloromethyl)pyridin-3-ol (CAS 1353877-94-7)
- (1R,2r)-2-(methoxycarbonyl)cyclopentanecarboxylic acid (CAS 111138-68-2)
- 2-(4-Aminophenyl)-3-imino-2,3-dihydro-1h-pyrazole-4-carboxamide (CAS 1252446-59-5)
- 1-(2,4-Dichlorophenyl)-4-oxocyclohexanecarboxylic Acid (CAS 1408058-11-6)
- Clascoterone Impurity 11 (CAS 82427-84-7)
- 0147AD 1185115-81-4 3-(Cyclohexylmethoxy)pyrrolidine hydrochloride C11H22ClNO (CAS 1185115-81-4)
- (R)-Ethyl 2-(1-((tert-butoxycarbonyl)amino)ethyl)thiazole-4-carboxylate (CAS 111946-75-9)
- 4-((4-Methylpyrimidin-2-yl)thio)cyclohexan-1-amine (CAS 1344272-26-9)
- 3-Amino-N,N-diethyl-4-(methylamino)benzenesulfonamide (CAS 49804-44-6)
- Neuropeptide K, porcine (CAS 106441-70-7)
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