3-Methoxy-2-(pyrrolidin-2-yl)pyridine CAS 1150617-89-2
| CAS No. | 1150617-89-2 |
| Molecular Formula | C10H14N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Methoxy-2-(pyrrolidin-2-yl)pyridine (CAS 1150617-89-2) is a high-purity analytical reference standard with the molecular formula C10H14N2OHCl and a molecular weight of 214.69 g/mol.
The molecular framework of 3-Methoxy-2-(pyrrolidin-2-yl)pyridine (C10H14N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Methoxy-2-(pyrrolidin-2-yl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O HCl |
| Molecular Weight | 214.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 1-(2-Methoxy-6-(methylsulfonyl)phenyl)piperazine (CAS 1000018-42-7)
- 6-methoxy-1-methyl-1H-1,3-benzodiazol-7-amine (CAS 1000202-26-5)
- 2-Methoxy-3-(trifluoromethyl)benzaldehyde (CAS 1000339-54-7)
- 1-Methoxy-3-methyl-5-(trifluoromethoxy)benzene (CAS 1000339-56-9)
- 5-Methoxy-7-methyl-1H-indazole-3-carbaldehyde (CAS 1000340-55-5)
- 5-Methoxy-7-methyl-1H-indazole-3-carboxylic acid (CAS 1000340-57-7)
- 5-Methoxy-6-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-90-8)
- 6-Methoxy-4-nitro-1H-indazole (CAS 1000341-08-1)
Recommended Standards
- 4-(Benzo[b]thiophen-3-yl)butanal (CAS 1342056-69-2)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-nitro-1H-indazole (CAS 150149-16-9)
- 6-Amino-4-(4-bromophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 89607-40-9)
- 2-(Pyrrolidin-3-yl)-1,2,3,4-tetrahydroisoquinoline dihydrochloride (CAS 1220017-74-2)
- 3-(4-(Trifluoromethoxy)benzyl)azetidine hydrochloride (CAS 1394688-94-8)
- Pyrrolo[2,1-b]thiazole-6-carboxylic acid (CAS 956293-18-8)
- SANT-2 (CAS 329196-48-7)
- 2-(Pentan-2-yl)isoindoline-1,3-dione (CAS 61345-59-3)
- Eltrombopag Impurity 158 (CAS CATO-C4X-1198158)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
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