Eltrombopag Impurity 158 CAS CATO-C4X-1198158

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1198158
Molecular FormulaC8H11N3O
Molecular Weight165.19 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Eltrombopag Impurity 158 CAS CATO-C4X-1198158 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Eltrombopag Impurity 158 (CAS CATO-C4X-1198158) is a certified pharmaceutical impurity reference standard with the molecular formula C8H11N3O and a molecular weight of 165.19 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Eltrombopag Impurity 158 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 165.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC8H11N3O
Molecular Weight165.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms3

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