5-((Trifluoromethyl)thio)pyridin-2-amine CAS 1153767-57-7
| CAS No. | 1153767-57-7 |
| Molecular Formula | C6H5F3N2S |
| Molecular Weight | 194.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-((Trifluoromethyl)thio)pyridin-2-amine (CAS 1153767-57-7), molecular formula C6H5F3N2S and molecular weight 194.18 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H5F3N2S, 5-((Trifluoromethyl)thio)pyridin-2-amine contains a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 194.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5F3N2S |
| Molecular Weight | 194.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 4-((Trifluoromethyl)thio)pyridin-3-amine (CAS 1153766-90-5)
- 2-((Trifluoromethyl)thio)pyridin-3-amine (CAS 1153767-00-0)
- 6-((Trifluoromethyl)thio)pyridin-3-amine (CAS 1153767-25-9)
- 3-((Trifluoromethyl)thio)pyridin-2-amine (CAS 1204234-81-0)
- 3-((Trifluoromethyl)thio)pyridin-4-amine (CAS 1204235-21-1)
- 2-(Trifluoromethyl)-5,6-dihydro-4H-pyrrolo[3,4-d]thiazole (CAS 1245915-62-1)
- 5-(Trifluoromethyl)thiophene-2-carboximidamide (CAS 1260663-11-3)
- 5-((Trifluoromethyl)thio)pyridin-3-amine (CAS 1935597-56-0)
Recommended Standards
- 7-Methoxy-2,3-dihydrobenzo[b][1,4]dioxine-6-carbaldehyde (CAS 116757-66-5)
- 4-Methoxycarbonyl-3-methyl-benzoicacid (CAS 116934-87-3)
- 5-(3-Hydroxy-3-methylbut-1-yn-1-yl)furan-2-carboxylic acid (CAS 1177362-04-7)
- 3-(2-Methoxy-2-oxoethyl)benzoic acid (CAS 113496-14-3)
- 4-Hydroxy-1H-imidazole-5-carbothioamide (CAS 71644-33-2)
- 1-Oxa-6-azaspiro[3.3]heptane Hydrochloride (CAS 1359704-67-8)
- 2-(4-(Trifluoromethyl)phenyl)thiazole-4-carbonyl chloride (CAS 857284-28-7)
- Ethyl 5-chloro-1H-imidazole-4-carboxylate (CAS 76182-29-1)
- 6-Bromo-4-nitropyridine-2-sulfonyl chloride (CAS 1393533-63-5)
- 7-Chloro-2-iodothiazolo[5,4-d]pyrimidine (CAS 1909309-71-2)
- 2-(Difluoromethyl)-6-fluoro-3-iodopyridine-5-carboxylic acid (CAS 1805438-38-3)
- Testosterone Impurity 12 (CAS CATO-C4X-132612)
- (4S)-1-Fmoc-4-methyl-L-proline (CAS 1228577-03-4)
- Semaglutide impurity 57 (CAS 2773558-06-6)
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