3-Amino-4-fluoro-N-(pyridin-3-yl)benzamide CAS 1154153-05-5
| CAS No. | 1154153-05-5 |
| Molecular Formula | C12H10FN3O |
| Molecular Weight | 231.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Amino-4-fluoro-N-(pyridin-3-yl)benzamide (CAS 1154153-05-5), molecular formula C12H10FN3O and molecular weight 231.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Amino-4-fluoro-N-(pyridin-3-yl)benzamide (C12H10FN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Amino-4-fluoro-N-(pyridin-3-yl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10FN3O |
| Molecular Weight | 231.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 5-Amino-3-[(4-fluoro-3-methylphenyl)amino]-1H-pyrazole-4-carbonitrile (CAS 1030827-94-1)
- Methyl 5-amino-2-(methylsulfonyl)pyrimidine-4-carboxylate (CAS 1780608-62-9)
- 3-Amino-4-((4-fluorophenyl)diazenyl)phenol (CAS 680580-18-1)
- 3-Amino-6-(4-fluorophenyl)picolinamide (CAS 917758-83-9)
- 5-Amino-2-fluoro-N-(pyridin-3-yl)benzamide (CAS 896160-37-5)
- n-(2-Amino-4-fluorophenyl)pyridine-2-carboxamide (CAS 926248-26-2)
- N-(3-amino-4-fluorophenyl)isonicotinamide (CAS 926227-55-6)
- N-(3-amino-4-fluorophenyl)nicotinamide (CAS 926241-61-4)
Recommended Standards
- 4-(Methoxysulfamoyl)benzoic acid (CAS 1087784-72-2)
- 2-[[5-(Ethoxymethyl)-1,3,4-thiadiazol-2-yl]amino]-2-oxoacetic acid (CAS 1158780-25-6)
- 5-(Cyclopropylsulfamoyl)furan-2-carboxylic acid (CAS 1087784-27-7)
- 1-Methanesulfonyl-4-methoxy-2-nitrobenzene (CAS 1187658-92-9)
- (5Z)-5-[(Dimethylamino)methylidene]-4-methyl-3-(4-nitrophenyl)-2,5-dihydrofuran-2-one (CAS 338976-32-2)
- (2-Chlorophenyl)(3-chlorophenyl)methanol (CAS 126517-23-5)
- 5-(Pyridin-4-yl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1086380-39-3)
- N-(3-bromophenyl)azetidine-3-carboxamide (CAS 1507883-21-7)
- 7-Fluoro-6-methoxyquinolin-4(1H)-one (CAS 948573-52-2)
- Anthracene-1,8-dicarboxylic acid (CAS 38378-77-7)
- N-Methylhexahydrocyclopenta[c]pyrrol-2(1H)-amine (CAS 54528-01-7)
- (R)-Methyl 3-methyl-2-oxooxazolidine-4-carboxylate (CAS 286844-99-3)
- Ribociclib Impurity 16 (CAS CATO-C4X-310016)
- [Formaldehyde Schiff-base]-Semaglutide Impurity 136 X TFA Salt (CAS CATO-C4X-2226136)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com