4-Chloro-6-fluoro-2-(methylthio)-5-(trifluoromethyl)pyrimidine CAS 115441-09-3
| CAS No. | 115441-09-3 |
| Molecular Formula | C6H3ClF4N2S |
| Molecular Weight | 246.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-6-fluoro-2-(methylthio)-5-(trifluoromethyl)pyrimidine.
CATO supplies 4-Chloro-6-fluoro-2-(methylthio)-5-(trifluoromethyl)pyrimidine (CAS 115441-09-3), a certified reference material (molecular formula C6H3ClF4N2S, MW 246.61 g/mol) for analytical method development and quality control.
Owing to a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, an aromatic ring system, 4-Chloro-6-fluoro-2-(methylthio)-5-(trifluoromethyl)pyrimidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-6-fluoro-2-(methylthio)-5-(trifluoromethyl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3ClF4N2S |
| Molecular Weight | 246.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylic acid methyl ester (CAS 175137-27-6)
- Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)amino)acetate (CAS 859307-58-7)
- 5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole (CAS 1076197-51-7)
- 4-Chloro-6-methyl-7-(trifluoromethyl)quinazoline (CAS 1160994-15-9)
- 3-Chloro-7-(trifluoromethyl)quinolin-4-amine (CAS 1203579-71-8)
- 4-(4-Chloro-3-fluoro-2-hydroxyphenyl)-4-oxobutanoic acid (CAS 1208265-79-5)
- 2-Chloro-4-(trifluoromethyl)quinolin-7-amine (CAS 1416439-79-6)
- 4-Chloro-2-methyl-6-(trifluoromethyl)quinazoline (CAS 1422284-63-6)
Recommended Standards
- 8-Chloro-2-(difluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid (CAS 2514942-10-8)
- 3-(3-Chloropropanoyl)-1-(3,3,3-trifluoropropyl)urea (CAS 1340452-19-8)
- 7-(Difluoromethyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carbonyl chloride (CAS 886494-08-2)
- Ethyl 6-amino-2-chloro-5-nitropyrimidine-4-carboxylate (CAS 15949-13-0)
- N-(2-Methoxyphenyl)pyridin-3-amine (CAS 1028223-83-7)
- 7-((2-Chloro-6-fluorobenzyl)thio)-3-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 1060203-38-4)
- Ethyl 3-(1H-imidazol-2-yl)propanoate (CAS 172499-76-2)
- 3-chloro-4-isopropoxybenzenesulfonyl chloride (CAS 1016509-32-2)
- 1-(2-Methoxybenzoyl)-1,4-diazepane (CAS 61903-19-3)
- 5-Methylhexan-1-amine hydrochloride (CAS 1333628-05-9)
- 6-Iodo-3-methylindolin-2-one (CAS 2092716-76-0)
- 2-(2-Fluoro-4-(isopropylamino)phenyl)quinoline-6-carboxylic acid (CAS 921211-16-7)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)ethan-1-amine (CAS 771571-63-2)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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