4-Amino-2-chloro-3-fluorobenzeneboronic acid pinacol ester, 97% CAS 1154740-65-4
| CAS No. | 1154740-65-4 |
| Molecular Formula | C12H16BClFNO2 |
| Molecular Weight | 271.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Amino-2-chloro-3-fluorobenzeneboronic acid pinacol ester, 97%.
CATO supplies 4-Amino-2-chloro-3-fluorobenzeneboronic acid pinacol ester, 97% (CAS 1154740-65-4), a certified reference material (molecular formula C12H16BClFNO2, MW 271.52 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H16BClFNO2, 4-Amino-2-chloro-3-fluorobenzeneboronic acid pinacol ester, 97% contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 271.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Amino-2-chloro-3-fluorobenzeneboronic acid pinacol ester, 97% meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16BClFNO2 |
| Molecular Weight | 271.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- 1-(3,4-Dichlorophenyl)-1,4,5,6-tetrahydro-6-oxo-3-pyridazinecarboxylic acid (CAS 926254-12-8)
- 1-Ethyl-6-fluoro-2-methylquinolin-4(1H)-one (CAS 1209702-89-5)
- 4-Amino-3-(pyridin-4-yl)butanoic acid (CAS 1267266-77-2)
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