6-Bromo-5-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one CAS 1154740-66-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-5-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one.

6-Bromo-5-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 1154740-66-5) is a high-purity analytical reference standard with the molecular formula C8H5BrClNO2 and a molecular weight of 262.49 g/mol.

Structurally, 6-Bromo-5-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one (C8H5BrClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 262.49 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Bromo-5-chloro-2H-benzo[b][1,4]oxazin-3(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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